WorldCat Identities

Prymula, Roman 1964-

Overview
Works: 14 works in 16 publications in 2 languages and 22 library holdings
Roles: Author
Publication Timeline
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Most widely held works by Roman Prymula
Biologický a chemický terorismus : informace pro každého by Roman Prymula( Book )

2 editions published in 2002 in Czech and held by 4 WorldCat member libraries worldwide

SARS : syndrom akutního respiračního selhání by Roman Prymula( Book )

2 editions published in 2006 in Czech and held by 3 WorldCat member libraries worldwide

Epi Info verze 5.01 : Uživatelská příručka by Jiří Beran( Book )

1 edition published in 1993 in Czech and held by 2 WorldCat member libraries worldwide

Očkování v České republice, Armádě ČR a v armádách NATO : učební text pro vysokoškolskou výuku by Roman Prymula( Book )

1 edition published in 2008 in Czech and held by 2 WorldCat member libraries worldwide

Vybrané kapitoly ze zdravotnického managementu : zdravotnické systémy by Roman Prymula( Book )

1 edition published in 1999 in Czech and held by 2 WorldCat member libraries worldwide

Safety, reactogenicity and immunogenicity of two investigational pneumococcal protein-based vaccines results from a randomized phase II study in infants by Roman Prymula( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

Introduction: Vaccination with formulations containing pneumococcal protein antigens such as pneumolysin toxoid (dPly) and histidine-triad protein D (PhtD) may extend serotype-related protection of pneumococcal conjugate vaccines (PCVs) against Streptococcus pneumoniae. Methods: This phase II, multi-center, observer-blind trial conducted in Europe (NCT01204658) assessed 2 investigational vaccines containing 10 serotype-specific polysaccharide conjugates of PHiD-CV and either 10 or 30 mu g of dPly and PhtD each. Infants randomized 1:1:1:1 received 4 doses of PHiD-CV/dPly/PhtD-10, PHiD-CV/c1Ply/PhtD-30, PHiD-CV, or 13-valent PCV (PCV13), co-administered with DTPa-HBV-IPV/Flib, at ages 2, 3, 4 and 12-15 months. Occurrences of fever>40.0 degrees C following primary vaccination with PHiD-CV/dPly/PhtD vaccines compared to PHiD-CV (non-inferiority objective), dose superiority, safety and immunogenicity were assessed. Results: 575 children received primary vaccination, and 564 booster vaccination. The non-inferiority objective was met; no fever>40.0 degrees C causally related to vaccination was reported during primary vaccination. Incidence of adverse events appeared similar between the 3 PHiD-CV groups. Serious adverse events were reported in 13, 9, 21 (1 related to vaccination), and 17 children in the PHiD-CV/c1Ply/PhtD-10, PHiD-CV/dPly/PhtD-30, PHiD-CV, and PCV13 groups, respectively. PHiD-CV/dPly/PhtD-30 was superior to PHiD-CV/c1Ply/PhtD-10 in terms of post-dose 3 anti-Ply and Anti-PhtD antibody levels. Anti-Ply and anti-PhtD antibody levels were higher in both PHiD-CV/dPly/PhtD groups than in controls and increased from post-primary to post-booster timepoint. Post-primary and booster vaccination, for each PHiD-CV serotype,>= 98.5% of participants in PHiD-CV/dPly/PhtD groups had antibody concentrations>= 0.2 mu g/mL, except for 6B (>= 72.3%) and 23 F (>= 82.7%) post-primary vaccination. Similar results were observed in the PHiD-CV group. Immune responses to protein D and DTPa-HBV-IPV/Hib were within similar ranges for the 3 PHiD-CV groups. Conclusion: Both PHiD-CV/dPly/PhtD formulations co-administered with DTPa-HBV-IPV/Hib in infants were well-tolerated and immunogenic for dPly and PhtD antigens, while immune responses to serotype-specific, protein D and co-administered antigens did not appear altered in comparison to PHiD-CV group
Základy managementu ve zdravotnictví <<I=01>> by Roman Prymula( Book )

1 edition published in 1995 in Czech and held by 1 WorldCat member library worldwide

Influenza vaccination in the elderly( )

1 edition published in 2018 in English and held by 1 WorldCat member library worldwide

ABSTRACT: Seasonal influenza is a prevalent and serious annual illness resulting in widespread morbidity and economic disruption throughout the population; the elderly and immunocompromised are particularly vulnerable to serious sequelae and mortality. The changing demographics worldwide to an aging society have important implications for public health policy and pharmaceutical innovations. For instance, primary prevention via immunization is effective in reducing the burden of influenza illness among the elderly. However, the elderly may be insufficiently protected by vaccination due to the immunosenescence which accompanies aging. In addition, vaccine hesitancy among the younger populations increases the likelihood of circulating infectious diseases, and thus concomitant exposure. While it is clear that the development of more immunogenic vaccines is an imperative and worthy endeavor, clinical trials continue to demonstrate that the current influenza vaccine formulation remains highly effective in reducing morbidity and mortality when well matched to circulating strains
Základy managementu ve zdravotnictví <<II=02>> : zdravotnické systémy( Book )

1 edition published in 1995 in Czech and held by 1 WorldCat member library worldwide

Rotavirus vaccination in Central Europe( )

1 edition published in 2013 in English and held by 1 WorldCat member library worldwide

Základy managementu ve zdravotnictví I. by Roman Prymula( Book )

1 edition published in 1995 in Czech and held by 1 WorldCat member library worldwide

Základy managementu ve zdravotnictví II( Book )

1 edition published in 1995 in Czech and held by 1 WorldCat member library worldwide

Immunization of high-risk paediatric populations Central European Vaccination Awareness Group (CEVAG) recommendations( )

1 edition published in 2014 in English and held by 1 WorldCat member library worldwide

 
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Audience Level
1
  Kids General Special  
Audience level: 0.96 (from 0.88 for Influenza ... to 0.99 for Vybrané k ...)

Associated Subjects
Alternative Names
Roman Prymula Czech epidemiologist and doctor

Languages
Czech (11)

English (5)