WorldCat Identities

Thurnher, Martin 1844-1922

Works: 3 works in 4 publications in 2 languages and 25 library holdings
Roles: Author
Publication Timeline
Most widely held works by Martin Thurnher
Mevalonate metabolism governs cancer immune surveillance( )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

ABSTRACT: The metabolic reprogramming that drives immunity engages the mevalonate pathway for cholesterol biosynthesis and protein prenylation. The importance of tight regulation of this metabolic route is reflected by the fact that too low activity impairs cellular function and survival, whereas hyperactivity can lead to malignant transformation. Here, we first address how mevalonate metabolism drives immunity and then highlight ways of the immune system to respond to both, limited and uncontrolled flux through the mevalonate pathway. Immune responses elicited by mevalonate pathway dysregulation may be harnessed to increase the clinical efficacy of current cancer therapy regimens
Audience Level
Audience Level
  Kids General Special  
Audience level: 0.89 (from 0.88 for Mevalonate ... to 0.96 for Strategisc ...)

Alternative Names
Martin Thurnher Austrian politician

Martin Thurnher avstrijski politik

Martin Thurnher österreichischer Politiker

Martin Thurnher osztrák politikus

Martin Thurnher pedagoog uit Oostenrijk (1844-1922)

Martin Thurnher politicien autrichien

Martin Thurnher político austríaco

Martin Thurnher rakouský politik