WorldCat Identities

Amon, Angelika

Overview
Works: 4 works in 14 publications in 3 languages and 172 library holdings
Roles: Author
Classifications: QH581.2, 571.6
Publication Timeline
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Most widely held works by Angelika Amon
Molecular cell biology by James E Darnell( Book )

11 editions published between 2013 and 2016 in 3 languages and held by 170 WorldCat member libraries worldwide

With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on key experiments, Molecular Cell Biology has justly earned an impeccable reputation as an exciting and authoritative text. Avoiding an encyclopedic approach, the book grounds its coverage in the experiments that define our understanding of cell biology, engaging students with the exciting breakthroughs that define the field's history and point to its future. The authors, all world-class researchers and teachers, incorporate medically relevant examples where appropriate to help illustrate the connections between cell biology and health and human disease. -- Publisher
Causes and consequences of aneuploidy by Angelika Amon( Visual )

1 edition published in 2008 in English and held by 1 WorldCat member library worldwide

(CIT): For the building of an organism, it is essential that cell division occurs in a precise and orderly manner. Deciphering the regulatory networks that ensure accurate segregation of the genetic material is thus vital to understanding both normal cell division and abnormal cell division that leads to cancer and birth defects. My laboratory investigates the controls that ensure that chromosome segregation occurs accurately and that the process is orchestrated with other cellular events. In particular, our work determined the role of the protein phosphatase Cdc14 in the final stages of the eukaryotic cell cycle, called exit from mitosis. During exit from mitosis, cells complete the chromosome segregation phase and get ready for the next duplication phase. We showed that the protein phosphatase Cdc14 is a key trigger of this transition and that its activation during chromosome segregation is essential for exit from mitosis to occur. Furthermore, we elucidated the intricate regulation of Cdc14 by nucleolar sequestration. This work has not only served as a paradigm as to how the regulation of the subcellular localization of a protein controls a key cell cycle transition but also has shed light onto how exit from mitosis is coordinated with other cellular events such as chromosome segregation and mitotic spindle function. We also investigate what happens to yeast cells that, defying the odds, acquired extra chromosomes and hence are aneuploid. We discovered a set of phenotypes common to aneuploid cells that are independent of the chromosomal identity. These phenotypes include a delay in cell cycle progression, a transcriptional signature and effects on cellular homeostasis. The characterization of these cells as well as initial studies on aneuploid mammalian cells will be presented. Dr. Amon conducted her Ph.D. work in the laboratory of Dr. Kim Nasmyth at the Institute of Molecular Pathology in Vienna and obtained her Ph.D. from the University of Vienna in 1993. After a year in Dr. Franz Klein's lab at the Institute of Botany at the University of Vienna, investigating the mechanisms of meiotic recombination, she joined the laboratory of Dr. Ruth Lehmann at the Whitehead Institute, studying how germ cells are formed. During her tenure as a Whitehead fellow, Dr. Amon's laboratory investigated the mechanism of chromosome segregation in budding yeast. Specifically, her lab identified the protein that triggers chromosome segregation by inducing the degradation of a chromosome segregation inhibitor called Securin. In 1999, Dr. Amon joined the faculty of the Department of Biology and the Center for Cancer Research at MIT. In 2000, she was selected to become an Investigator of the Howard Hughes Medical Institute. In 2002, Dr. Amon was promoted to Associate Professor and awarded tenure in 2004. At the Center for Cancer Research Dr. Amon, studies the molecular mechanisms governing mitotic and meiotic chromosome segregation. In particular, her lab deciphered the molecular mechanisms that control the final stages of mitosis and discovered the molecular mechanisms that generate the meiotic chromosome segregation pattern. For more information, visit http://www.hhmi.org/research/investigators/amon_bio.html The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide
Aneuploidy and cancer : a complicated relationship( Visual )

1 edition published in 2017 in English and held by 1 WorldCat member library worldwide

(CIT): NCI's Center for Cancer Research (CCR) Eminent Lecture Dr. Amon received her B.S. and Ph.D. from the University of Vienna. She completed a two-year post-doctoral fellowship with Ruth Lehmann at the Whitehead Institute and was subsequently named a Whitehead Fellow for three years. In 1999, she joined the MIT Koch Institute for Integrative Cancer Research and the Department of Biology where she holds the Kathleen and Curtis Marble Chair for Cancer Research. Dr. Amon"s honors include the 2003 Alan T. Waterman Award, the 2007 Paul Marks Prize, the 2008 National Academy of Sciences Molecular Biology Award, and the 2013 Ernst Jung Prize for Medicine. Dr. Amon is a Member of the Howard Hughes Medical Institute, the National Academy of Sciences, the Austrian Academy of Science, and a Foreign Associate to EMBO. At the Koch Institute, Dr. Amon studies the molecular mechanisms that control cell growth and division with a focus on the pathways that regulate chromosome segregation. Dr. Amon also studies how errors in this process lead to diseases such as cancer and Down Syndrome and how they impact the aging process
Role of polo-like kinase CDC5 in programming meiosis I chromosome segregation by Brian H Lee( )

1 edition published in 2003 in English and held by 0 WorldCat member libraries worldwide

 
Audience Level
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Audience Level
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Audience level: 0.58 (from 0.58 for Molecular ... to 1.00 for Role of po ...)

Associated Subjects
Alternative Names
Angelika Amon ahli biologi asal Austria

Angelika Amon austriacko-amerykańska biolożka molekularna i cytolożka

Angelika Amon Austrian American molecular and cell biologist and academic

Angelika Amon biologe uit Oostenrijk

Angelika Amon österreichische Zellbiologin und Genetikerin

Ангелика Амон

أنجيليكا آمون عالمة نمساوية-أمريكية

Languages