WorldCat Identities

MacDonald, Jeffrey R. 1943-

Overview
Works: 33 works in 83 publications in 6 languages and 6,165 library holdings
Genres: Biography  Case studies  Handbooks, manuals, etc  Academic theses 
Roles: Author, Thesis advisor
Classifications: HV6248.M178, 364.15230924
Publication Timeline
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Most widely held works about Jeffrey R MacDonald
 
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Most widely held works by Jeffrey R MacDonald
Department of emergency medicine guideline manual : policies and procedures by Jeffrey R MacDonald( Book )

3 editions published in 1979 in English and held by 96 WorldCat member libraries worldwide

The Jeffrey MacDonald murder case( Visual )

1 edition published in 1999 in English and held by 3 WorldCat member libraries worldwide

Presents the case of Capt. Jeffrey MacDonald, a Green Beret surgeon accused of savagely murdering his pregnant wife and two young daughters in 1970. First cleared of the murders by a military judge, MacDonald was tried and convicted almost ten years later. The case inspired the book Fatal vision by Joe McGinniss, who was successfully sued for fraud by MacDonald. Documentary includes news footage, archival photographs, and interviews with MacDonald, his attorney, investigators, prosecutors, a juror, family members and supporters who continue to maintain his innocence
Othello( Visual )

1 edition published in 1988 in English and held by 2 WorldCat member libraries worldwide

Colon cancer diagnosis using NMR spectra of urine by Hannah T Medford( )

1 edition published in 2006 in English and held by 1 WorldCat member library worldwide

Colon cancer is the third most common cancer in people, and early diagnosis is critical to survival. This study investigates the efficacy of using metabolomic technology in diagnosing colon cancer in a mouse model. Urine from a genetically defined population of mice was analyzed by NMR spectrometry, after carcinogen exposure and categorization for tumor development based on histological examination. The NMR spectra were then analyzed by statistical methods of classification to determine if colon tumors result in changes to the metabolites secreted in urine that can be detected by NMR spectrometry. Different statistical analyses were also compared to determine which is most effective at retrieving information from the NMR data. Principal Component Analysis (PCA), a popular analysis for metabolomic data, is ineffective on this data set. Support Vector Machine (SVM) reveals six significant components, which when entered into PCA results in clear separation of normal and tumor-bearing mice
Fatal vision by Joe McGinniss( Book )

1 edition published in 1983 in English and held by 1 WorldCat member library worldwide

A documented book on a doctor in the Green Berets who was convicted of the slaying of his pregnant wife and two small daughters
Cerebral metabolism of ethanol-derived acetate a metabolic basis for dependence? by Peter C Nicholas( )

1 edition published in 2006 in English and held by 1 WorldCat member library worldwide

Alcoholism is a tremendous health problem throughout the world. Ethanol is a unique drug that is consumed in large quantities for pharmacologic effect, reaching blood concentrations as high as 100mM. Ethanol is eliminated almost exclusively via oxidation to acetate in the liver, and nearly all of the ethanol-derived acetate is released into the blood where it travels to other organs, including the brain, for use as an energy source. Thus ethanol directly alters metabolism in the liver, and causes the production of large amounts of acetate which may serve as a substrate for brain, possibly contributing to intoxication and dependence. This dissertation describes two separate approaches to study the metabolic effects of ethanol. First, 1H NMR-based metabolomic analysis of endogenous metabolites revealed decreased lactate and alanine, and increased acetate and ketone bodies due to ethanol. These results provided new insights regarding the effect of ethanol on gluconeogenesis. In addition, we determined that ethyl glucuronide (EtG), a unique metabolite of ethanol, produces a characteristic NMR signal. EtG is formed within hours of ethanol dosing, and remains elevated during a 4 day binge exposure. The antioxidant BHT appears to reduce formation of EtG during a 4 day exposure to ethanol. Our second approach used 13C-enriched tracers along with 13C NMR to measure brain metabolism of ethanol-derived acetate. Our hypothesis was that cerebral metabolism of acetate released from the liver during ethanol oxidation perturbs cerebral metabolism, and thereby contributes to neuroadaptation associated with alcohol dependence and withdrawal. Using a single dose of [2-13C] ethanol intragastrically, we found carbons derived from ethanol are rapidly incorporated into brain amino acids glutamate, glutamine, and GABA. Next, we investigated whether a 10 day exposure to ethanol would increase cerebral utilization of acetate. We found that acetate metabolism was not increased, most likely because transport into brain astrocytes was not increased. We did find, however, that ethanol induced significant changes in metabolism of GABA, and we speculate that this may reflect neuroadaptations that produce tolerance to ethanol
Dr. Jeffrey MacDonald : the truth( Book )

1 edition published in 1985 in English and held by 0 WorldCat member libraries worldwide

 
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Audience level: 0.16 (from 0.06 for Crimes of ... to 1.00 for Dr. Jeffre ...)

Alternative Names
Jeffrey MacDonald

Jeffrey MacDonald US-amerikanischer Mrder

Mac Donald, Jeffrey R. 1943-

MacDonald, Jeffrey 1943-

Languages
Covers
The journalist and the murdererFatal justice : reinvestigating the MacDonald murdersFlame-out : from prosecuting Jeffrey MacDonald to serving time to serving tablesScales of justice : the murders of Colette, Kimberley & Kristen MacDonaldScales of justice : the Jeffrey MacDonald story