WorldCat Identities

Agre, Peter 1949-

Overview
Works: 11 works in 31 publications in 1 language and 956 library holdings
Genres: Conference proceedings 
Roles: Editor
Classifications: QP552.A65, 572.696
Publication Timeline
Key
Publications about  Peter Agre Publications about Peter Agre
Publications by  Peter Agre Publications by Peter Agre
Most widely held works by Peter Agre
Aquaporins by Eric Beitz ( )
9 editions published between 2008 and 2009 in English and held by 423 WorldCat member libraries worldwide
The aquaporin field has matured at an exceptionally fast pace, and we are at the verge of developing serious strategies to modulate aquaporin function directly or via regulatory networks. This text covers recent developments, from basic research to potential pharmacological use
Aquaporins by Dale J Benos ( Book )
7 editions published in 2001 in English and held by 222 WorldCat member libraries worldwide
Aquaporins summarizes the present knowledge in this expanding field of research, starting with the structural analysis of water channel proteins. Subsequent chapters begin with mammalian aquaporins, examining physiology and pathophysiology, analysis of knock-out model animals, and the regulation of aquaporin function. Also covered is the distribution and regulation of aquaporins in plants and the function of water and glycerol channels in microbial systems
Red blood cell membranes : structure, function, clinical implications ( Book )
4 editions published in 1989 in English and held by 167 WorldCat member libraries worldwide
Protein blood group antigens of the human red cell : structure, function, and clinical significance ( Book )
2 editions published in 1992 in English and held by 135 WorldCat member libraries worldwide
Brain water homeostasis ( Book )
2 editions published in 2004 in English and held by 2 WorldCat member libraries worldwide
Current topics in membranes ( Book )
2 editions published in 2001 in English and held by 2 WorldCat member libraries worldwide
Aquaporins summarizes the present knowledge in this expanding field of research, starting with the structural analysis of water channel proteins. Subsequent chapters begin with mammalian aquaporins, examining physiology and pathophysiology, analysis of knock-out model animals, and the regulation of aquaporin function. Also covered is the distribution and regulation of aquaporins in plants and the function of water and glycerol channels in microbial systems
Aquaporin water channels--from atomic structure to clinical medicine ( )
1 edition published in 2002 in English and held by 1 WorldCat member library worldwide
The water permeability of biological membranes has been a longstanding problem in physiology, but the proteins responsible for this remained unknown until discovery of the aquaporin 1 (AQP1) water channel protein. AQP1 is selectively permeated by water driven by osmotic gradients. The atomic structure of human AQP1 has recently been defined. Each subunit of the tetramer contains an individual aqueous pore that permits single-file passage of water molecules but interrupts the hydrogen bonding needed for passage of protons. At least 10 mammalian aquaporins have been identified, and these are selectively permeated by water (aquaporins) or water plus glycerol (aquaglyceroporins). The sites of expression coincide closely with the clinical phenotypes--ranging from congenital cataracts to nephrogenic diabetes insipidus. More than 200 members of the aquaporin family have been found in plants, microbials, invertebrates and vertebrates, and their importance to the physiology of these organisms is being uncovered
The importance of aquaporin water channel protein structures ( )
1 edition published in 2000 in English and held by 1 WorldCat member library worldwide
The history of the water channel and recent structural and functional analyses of aquaporins are reviewed. These ubiquitous channels are important for bacteria, plants and animals, exhibit a pronounced sequence homology and share functional as well as structural similarities. Aquaporins allow water or small specific solutes to pass unhindered, but block the passage of ions to prevent dissipation of the transmembrane potential. Besides advances in structure determination, recent experiments suggest that many of these channels are regulated by pH variations, phosphorylation and binding of auxiliary proteins
Progress on the structure and function of aquaporin 1 ( )
1 edition published in 1998 in English and held by 1 WorldCat member library worldwide
Life exists in water as universal solvent, and cells need to deal with its influx and efflux. Nature has accomplished the almost impossible, creating membrane channels with both a high flux and a high specificity for water. The first water channel was discovered in red blood cell membranes. Today known as aquaporin-1, this channel was found to be closely related to the major integral protein (MIP)1 of the eye lens. Cloning and sequencing of numerous related proteins of the MIP family revealed the widespread occurrence of such channels, suggesting an essential physiological function. Their structures hold the clues to the remarkable water channel activity, as well as to the arrangement of transmembrane segments in general. Recent medium-resolution three-dimensional electron microscopic studies determined a tetrameric complex with six tilted transmembrane helices per monomer. The helices within each monomer surround a central density formed by two interhelical loops implicated by mutagenesis in the water channel function. A combination of sequence analysis and assignment of the observed densities to predicted helices provides a basis for speculation on the nature of the water course through the protein. In particular, four highly conserved polar residues, E142-N192-N76-E17, are proposed to form a chain of key groups involved in the pathway of water flow through the channel
Aquaporin water channels from atomic structure to clinical medicine ( Visual )
1 edition published in 2005 in English and held by 1 WorldCat member library worldwide
 
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Alternative Names
Agre, P. 1949-
Agre, Peter C.
Agre, Peter Courtland 1949-
Languages
English (31)
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