WorldCat Identities

Dinarello, Charles A.

Overview
Works: 27 works in 69 publications in 2 languages and 1,113 library holdings
Genres: Conference proceedings 
Roles: Author, Editor
Classifications: RM282.C95, 616.5061
Publication Timeline
.
Most widely held works by Charles A Dinarello
Cytokines as potential therapeutic targets for inflammatory skin diseases by R Numerof( )
15 editions published between 2005 and 2006 in English and held by 487 WorldCat member libraries worldwide
Cytokines and cytokine receptors remain an area of great interest for the development of targeted therapies for cutaneous inflammatory diseases. Anti-TNF therapeutics have proven to be effective in the treatment of psoriasis, and clinical investigations have now begun for other cytokine-directed therapies, such as those targeting IFN-g, IL-12p40, and IL-18. In addition to therapeutics that target cytokines directly, strategies that target cytokine signaling pathways are in development. This book summarizes the findings of the 56th International Workshop of the Ernst Schering Research Foundation that focused on Cytokines as Potential Therapeutic Targets for Inflammatory Skin Diseases
Molecular mechanisms of fever ( Book )
10 editions published between 1998 and 2002 in English and held by 292 WorldCat member libraries worldwide
Pharmacology of cytokines by Alberto Mantovani( Book )
8 editions published between 2000 and 2007 in English and held by 145 WorldCat member libraries worldwide
The physiological and pathological effects of cytokines : from the proceedings of the Second International Workshop on Cytokines, held at Hilton Head Island, South Carolina, December 10-14, 1989 by International Workshop on Cytokines( Book )
5 editions published in 1990 in English and held by 117 WorldCat member libraries worldwide
Fever by Charles A Dinarello( Book )
1 edition published in 1980 in English and held by 22 WorldCat member libraries worldwide
Proinflammatory and anti-inflammatory cytokines in rheumatoid arthritis : a primer for clinicians by Charles A Dinarello( Book )
6 editions published between 1999 and 2002 in English and Undetermined and held by 17 WorldCat member libraries worldwide
Mechanisms of action of tumor necrosis factor antagonists : Canadian expert roundtable meeting, Banff, Alberta, Canada, November 28-30, 2003 ( Book )
2 editions published in 2005 in English and held by 8 WorldCat member libraries worldwide
Special issue, potential therapeutic uses of interleukin-1 ( Book )
1 edition published in 1989 in English and held by 6 WorldCat member libraries worldwide
Mechanisms of action of tumor necrosis factor antagonists ( )
2 editions published between 2004 and 2005 in English and held by 2 WorldCat member libraries worldwide
Mechanisms in the production of fever ( Visual )
1 edition published in 1981 in English and held by 2 WorldCat member libraries worldwide
Presents the physiology of the production of fever in children
Role of IL-1[beta] in type 2 diabetes ( )
1 edition published in 2010 in English and held by 1 WorldCat member library worldwide
To understand the role of inflammation as the fundamental cause of type 2 diabetes and specifically to examine the contribution of IL-1[beta]
The physiological and pathological effects of cytokines ( )
1 edition published in 1990 in English and held by 1 WorldCat member library worldwide
Interleucina-1, Interleucina-6 y factor de necrosis tumoral en sepsis neonatal by Javier Mancilla Ramirez( )
1 edition published in 1996 in Spanish and held by 1 WorldCat member library worldwide
Objetivo: determinar la capacidad del neonato septico para producir IL-1, IL6 y TNF, y relacionar sus niveles circulantes con la evolucion clinica. Material y metodos: se evaluaron 38 recien nacidos con sepsis hospitalizados en el Instituto Nacional de Perinatologia, y se midieron niveles plasmaticos de IL1, IL6 y factor de necrosis tumoral (TNF), mediante radioinmunoensayos especificos. Resultados: las tres citocinas se encontraron elevadas en comparacion con los niveles plasmaticas de 38 neonatos no septicos. Los niveles muy elevados IL-1 se relacionaron con mala evolucion y muerte. Conclusiones: se sugiere que IL-1, IL-6 y TNF que pueden ser utiles como predictores de la evolucion clinica de neonatos con sepsis grave(AU)
IL-1 family nomenclature ( )
1 edition published in 2010 in Undetermined and held by 1 WorldCat member library worldwide
Anti-cytokine therapies for inflammatory diseases ( Visual )
1 edition published in 1999 in English and held by 1 WorldCat member library worldwide
10th ISBP Symposium : October 7-9, 1992, Louisville, Ky., USA by International Society of Blood Purification( )
1 edition published in 1993 in English and held by 1 WorldCat member library worldwide
Anti-cytokine therapies for inflammatory diseases ( Visual )
1 edition published in 1999 in English and held by 1 WorldCat member library worldwide
Royal blue and black poster, with the print in a yellow/green or white. The only visual consists of wavy black and royal blue lines in the background
Potential therapeutic uses of interleukin-1 ( Book )
2 editions published in 1989 in English and held by 1 WorldCat member library worldwide
Proceedings of the International Workshop on Non-Lymphocytic Cytokines (2nd), Held in South Carolina on 10-14, December 1989: Progress in Leukocyte Biology. Volume 10B: The Physiological and Pathological Effects of Cytokines ( Book )
1 edition published in 1990 in English and held by 1 WorldCat member library worldwide
Cytokines are polypeptides synthesized by many cells which act on a variety of tissues by changing gene expression and cellular metabolism. The pro-inflammatory cytokines are a particular group of cytokines with molecular weights between 8,000 - 25,000 Daltons which appear to be synthesized primarily in association with disease states or during host perterbation. Some 'normal' physiologic events such as strenuous exercise or normal ovulation result in the synthesis of the pro-inflammatory cytokines. These polypeptides are very potent molecules which, at picomolar or even femtomolar concentrations, trigger a variety of responses in cells in vitro but similar concentrations may be effective in vivo when one considers the half-life, clearance and distribution of parenterally administered cytokines
La fosfatidilcolina induce un aumento en la produccion de interleucina-6 y mejora la sobrevida de ratas con sepsis neonatal por Klebsiella pneumoniae by Javier Mancilla Ramirez( )
1 edition published in 1995 in English and held by 1 WorldCat member library worldwide
Las infecciones por bacterias gram negativas son una de las primeras causas de muerte en el recien nacido. La depuracion de bacterias es deficiente en el neonato, situacion que aumenta la susceptibilidad a las infecciones. En este estudio se logro mejorar el patron de depuracion de Klebsiella pneumoniae en ratas wistar recien nacidas inoculadas por via IP con 800mg/k de fosfatidilcolina de soya (FC), en contraste con el grupo testigo inyectado con PBS(p<0.05). La sobrevida de los animales aumento (p<0.05), y los cambios leucocitarios se caracterizaron por una mayor leucocitosis y neutrofilia durante el pico de bacteremia en los animales tratados con FC. Los niveles circulantes de interleucina-6 fueron mayores en el grupo de FC, observandose ademas hematopoyesis extramedular de las series granulociticas (p<0.05) y de megacariocitos (p<0.01) en el bazo de las ratas del grupo de FC. No se observaron cambios significativos en los depositos de granulocitos en la medula osea de ambos grupos. La mejoria de la sobrevida, los cambios leucocitarios y los focos de hematopoyesis extramedular, parecen asociarse al aumento en la produccion de IL-6. Los resultados sugieren que la IL-6 participa en el mecanismo de proteccion; y que la FC induce en este modelo a septicemia experimental. La FC parece comportarse como un inmunomodulador inespecifico de la respuesta aguda a la infeccion bacteriana(AU)
 
moreShow More Titles
fewerShow Fewer Titles
Audience Level
0
Audience Level
1
  Kids General Special  
Audience level: 0.75 (from 0.00 for Mechanisms ... to 1.00 for Anti-cytok ...)
Alternative Names
Dinarello C. A
Dinarello, C.A. (Charles A.)
Languages
English (59)
Spanish (1)
Covers