WorldCat Identities

Morris, R. G. M. (Richard G. M.)

Overview
Works: 28 works in 78 publications in 3 languages and 3,921 library holdings
Genres: Conference papers and proceedings  Rules 
Roles: Author, Editor, Compiler
Classifications: BF311, 153
Publication Timeline
.
Most widely held works by R. G. M Morris
Parallel distributed processing : implications for psychology and neurobiology( Book )

10 editions published in 1989 in English and held by 331 WorldCat member libraries worldwide

Cognitive systems : information processing meets brain science by R. G. M Morris( Book )

21 editions published between 2005 and 2006 in English and Undetermined and held by 280 WorldCat member libraries worldwide

This book presents an overview of the exciting, truly multidisciplinary research by neuroscientists and systems engineers in the emerging field of cognitive systems, providing a cross-disciplinary examination of this cutting-edge area of scientific research. This is a great example of where research in very different disciplines touches to create a new emerging area of research. The book illustrates some of the technical developments that could arise from our growing understanding of how living cognitive systems behave, and the ability to use that knowledge in the design of artificial systems
Long-term potentiation : enhancing neuroscience for 30 years by T. V. P Bliss( Book )

8 editions published between 2003 and 2004 in English and held by 124 WorldCat member libraries worldwide

Lernen und Gedächtnis : neurobiologische Mechanismen by R. G. M Morris( Book )

5 editions published in 2013 in German and held by 88 WorldCat member libraries worldwide

Neuroscience : science of the brain by R. G. M Morris( Book )

1 edition published in 1995 in English and held by 9 WorldCat member libraries worldwide

Elements of a neurobiological theory of the hippocampus the role of activity-dependent synaptic plasticity in memory by R. G. M Morris( Book )

7 editions published in 2005 in English and Undetermined and held by 5 WorldCat member libraries worldwide

Prvi koraki v nevroznanost, znanost o možganih( Book )

1 edition published in 2007 in Slovenian and held by 5 WorldCat member libraries worldwide

Synaptic plasticity in health and disease : papers of a discussion meeting issue( Book )

2 editions published between 2013 and 2014 in English and held by 4 WorldCat member libraries worldwide

Distributable profit as an accounting concept : an historical and critical analysis by R. G. M Morris( Book )

2 editions published in 1988 in English and held by 2 WorldCat member libraries worldwide

Cortical plasticity : the representation of experience( Book )

1 edition published in 1998 in English and held by 2 WorldCat member libraries worldwide

Memory and the Hippocampus: elements of a neurobiological theory by R. G. M Morris( Book )

3 editions published in 2005 in English and held by 2 WorldCat member libraries worldwide

Annotation This title can be previewed in Google Books - http://books.google.com/books?vid=ISBN9789056293796
Memory Stability and Synaptic Plasticity by Guy Billings( )

1 edition published in 2009 in English and held by 1 WorldCat member library worldwide

Numerous experiments have demonstrated that the activity of neurons can alter the strength of excitatory synapses. This synaptic plasticity is bidirectional and synapses can be strengthened (potentiation) or weakened (depression). Synaptic plasticity offers a mechanism that links the ongoing activity of the brain with persistent physical changes to its structure. For this reason it is widely believed that synaptic plasticity mediates learning and memory. The hypothesis that synapses store memories by modifying their strengths raises an important issue. There should be a balance between the necessity that synapses change frequently, allowing new memories to be stored with high fidelity, and the necessity that synapses retain previously stored information. This is the plasticity stability dilemma. In this thesis the plasticity stability dilemma is studied in the context of the two dominant paradigms of activity dependent synaptic plasticity: Spike timing dependent plasticity (STDP) and long term potentiation and depression (LTP/D). Models of biological synapses are analysed and processes that might ameliorate the plasticity stability dilemma are identified. Two popular existing models of STDP are compared. Through this comparison it is demonstrated that the synaptic weight dynamics of STDP has a large impact upon the retention time of correlation between the weights of a single neuron and a memory. In networks it is shown that lateral inhibition stabilises the synaptic weights and receptive fields. To analyse LTP a novel model of LTP/D is proposed. The model centres on the distinction between early LTP/D, when synaptic modifications are persistent on a short timescale, and late LTP/D when synaptic modifications are persistent on a long timescale. In the context of the hippocampus it is proposed that early LTP/D allows the rapid and continuous storage of short lasting memory traces over a long lasting trace established with late LTP/D. It is shown that this might confer a longer memory retention time than in a system with only one phase of LTP/D. Experimental predictions about the dynamics of amnesia based upon this model are proposed. Synaptic tagging is a phenomenon whereby early LTP can be converted into late LTP, by subsequent induction of late LTP in a separate but nearby input. Synaptic tagging is incorporated into the LTP/D framework. Using this model it is demonstrated that synaptic tagging could lead to the conversion of a short lasting memory trace into a longer lasting trace. It is proposed that this allows the rescue of memory traces that were initially destined for complete decay. When combined with early and late LTP/D iii synaptic tagging might allow the management of hippocampal memory traces, such that not all memories must be stored on the longest, most stable late phase timescale. This lessens the plasticity stability dilemma in the hippocampus, where it has been hypothesised that memory traces must be frequently and vividly formed, but that not all traces demand eventual consolidation at the systems level
Soybean production systems used in West Tennessee, 1976 and 1981 by R. G. M Morris( )

1 edition published in 1983 in English and held by 1 WorldCat member library worldwide

Learning memory( Book )

1 edition published in 1988 in English and held by 1 WorldCat member library worldwide

Hippocampal NMDA receptors and synaptic plasticity : a role in information storage? by R. G. M Morris( Visual )

1 edition published in 1992 in English and held by 1 WorldCat member library worldwide

Unmasking the mysterious mechanisms of memory by R. G. M Morris( Visual )

1 edition published in 1992 in English and held by 1 WorldCat member library worldwide

The Pierian Spring by R. G. M Morris( )

1 edition published in 1992 in Undetermined and held by 1 WorldCat member library worldwide

N/A
The tagging and capture hypothesis of synaptic plasticity : the roles of calmodulin kinases and the phenomenon of behavioural tagging by Roger Lluis Redondo Pena( )

1 edition published in 2010 in English and held by 1 WorldCat member library worldwide

The aims of this thesis were (1) to learn about the identities of the molecules involved in the maintenance of long-term potentiation (LTP), and (2) to develop and test a behavioural paradigm capable of elucidating the interaction between these molecular processes and the persistence of long-term memories. By improving the stability of field recordings in in vitro electrophysiology, it was possible to investigate the molecular processes that determine the long-term changes in synaptic efficacy. In these experiments, the interactions between two convergent inputs onto the same neuronal population in the CA1 region of the hippocampus were monitored for over ten hours. Analytically powerful three-pathway protocols using sequential strong and weak tetanization in varying orders, and test stimulation over long periods of time after LTP-induction, enabled a pharmacological dissociation of potentially distinct roles of the calmodulin kinase (CaMK) pathways in LTP. This places constraints on the mechanisms by which synaptic potentiation, and possibly memories, become stabilized. The experiments show that tag setting is blocked by the CaMK inhibitor KN-93 that, at low concentration primarily blocks CaMKII, whereas a CaMKK inhibitor, STO-609, selectively limits the synthesis or the availability of plasticity related proteins (PRPs). To test whether memories can be subject to modulation by independent experiences, behavioural studies tested the possibility of lengthening the persistence of a relatively weak memory by pairing its induction with an event capable of inducing the synthesis of the required PRPs. Corticosterone-dependent stressful events like a cold swim proved to interfere and weaken spatial memories. On the other hand, the exploration of a novel environment succeeded in rescuing the decay of a weak memory. The effect of the exploration of the novel environment was dependent on NMDA and dopamine receptor activation, as well as protein synthesis. These results are discussed in relation to the synaptic tagging and capture hypothesis and a novel model of the neuronal mechanisms underlying synaptic plasticity is developed from them
The problem of the hippocampus and space by R. G. M Morris( Visual )

1 edition published in 1992 in English and held by 1 WorldCat member library worldwide

Cognitive flexibility in anorexia nervosa and bulimia nervosa( )

1 edition published in 2004 in English and held by 1 WorldCat member library worldwide

The aim of this study was to determine if there are differences in cognitive flexibility in anorexia nervosa and bulimia nervosa. Fifty-three patients withan eating disorder (34 with anorexia nervosa and 19 with bulimia nervosa) and 35 healthy controls participated in the study. A battery of neuropsychological tests for cognitive flexibility was used, including Trail Making B, the Brixton Test, Verbal Fluency, the Haptic Illusion Test, a cognitive shifting task (CatBat) and a picture set test. Using exploratory factor analysis, four factors were obtained: 1: Simple Alternation; 2: Mental Flexibility; 3: Perseveration; and 4: Perceptual Shift. Patients with anorexia nervosa had abnormal scores on Factors 1 and 4. Patients with bulimianervosa showed a different pattern, with significant impairments in Factors 2 and 4. These findings suggest that differential neuropsychological disturbance in the domain of mental flexibility/rigidity may underlie the spectrum of eating disorders
 
moreShow More Titles
fewerShow Fewer Titles
Audience Level
0
Audience Level
1
  Kids General Special  
Audience level: 0.48 (from 0.01 for Elements o ... to 0.87 for Synaptic p ...)

Cognitive systems : information processing meets brain science
Alternative Names
Morris, R. G. M.

Morris, R. G. M. 1948-

Morris, Richard.

Morris, Richard 1948-

Morris, Richard D. 1948-

Morris, Richard Donald 1948-

Morris, Richard G. 1948-

Morris, Richard G. M.

Morris, Richard G. M. 1948-

Morris, Richard Graham Michael 1948-

Richard G. Morris britischer Neurowissenschaftler

Richard G. Morris British neuroscientist

Richard G. Morris Brits bioloog

Richard G. Morris neurocientífico británico

Richard G. Morris neuroscientifique britannique

Richard G. Morris neuroscienziato britannico

ریچارد جی. موریس

リチャード・G・モリス

Languages
Covers
Long-term potentiation : enhancing neuroscience for 30 years