WorldCat Identities

Baldwin, Thomas O.

Overview
Works: 23 works in 75 publications in 1 language and 1,437 library holdings
Genres: Conference papers and proceedings 
Roles: Editor, Other, Author
Classifications: QP601, 572.645
Publication Timeline
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Most widely held works by Thomas O Baldwin
Molecular chaperones by G. H Lorimer( Book )

16 editions published in 1998 in English and held by 448 WorldCat member libraries worldwide

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 285 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Key Features * Catalysts of Protein Folding: Protein Disulfide Isomerases, Cis-trans Peptidyl Prolyl Isomerases * Accessory Proteins: Chaperonins, Cochaperonins, Pap Proteins, Sec Proteins * Physical methods for investigation of interactions between chaperones and their substances * Cotranslational protein folding, cell-free protein synthesis and associated methods
Bioluminescence and chemiluminescence( Book )

16 editions published between 1999 and 2000 in English and held by 275 WorldCat member libraries worldwide

Since the publication of Bioluminescence and Chemiluminescence, Part B, genes have been cloned that encode luciferases from an array of bioluminescent organisms, novel applications of these genes have been developed, and much has been learned of the fundamental chemistry, biochemistry, structural biology, and biophysics of these intriguing enzymes. New strategies for application of chemiluminescence technology have been developed and refined, promising to further reduce the need to use radioisotopes in basic research and clinical laboratory settings. Methods for detection of low levels of light continue to push the limits of detection, allowing ready monitoring in real time of intricate subcellular processes within living cells. This book affords a glimpse of the state of the art of a rapidly advancing field, and presents to users of these methods a detailed reference of current activities in the field. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences. Key Features @bul* Outlines the use of luminescent reporter technologies to monitor gene expression and protein trafficking * Describes the luminescence-based clinical assay technologies * Details the basic biochemistry, biophysics, and chemistry of light-emitting reactions that are critical for applications * Includes explanations of the instrumentation used for detection and quantification of low level light * Shows the new applications of luminescence-based technologies that result largely from broad advances in recombinant DNA technologies and nonscale methods
Chemical aspects of enzyme biotechnology : fundamentals by Thomas O Baldwin( Book )

14 editions published between 1990 and 1991 in English and held by 165 WorldCat member libraries worldwide

The Industry-University Cooperative Chemistry Program has sponsored seven previous international symposia covering a wide variety of topics of interest to industrial and academic chemists. The eighth IUCCP symposium, held March 19-22, 1990, at Texas A & M University, represents a deviation from the former symposia, in that it is the first of a two-symposium series dedicated to the rapidly moving new field of industrial biochemistry that has beco~e known as biotechnology. Biotechnology is really not a new discipline, but rather is a term coined to describe the new and exciting commercial applications of biochemistry. The development of the field of biotechnology is a direct result of recombinant DNA technology, which began in earnest about 15 years ago. Today, we can routinely do experiments that were inconceivable in the early 1970's. Only comparatively simple technology available even in small laboratories is required to synthesize a gene and from it, to produce vast amounts of biological materials of enormous commercial value. These technical developments and others have stimulated increased activities in the field of enzyme biotechnology, using enzymes to catalyze "unnatural" reactions to produce complex molecules with stereochemical precision. It is true today, we can readily produce DNA fragments that will encode any amino acid sequence that we might desire, but at this point, our foundation of basic knowledge falls short. The dream of "designer enzymes" is still a fantasy, but the current wave of research activity and exciting new developments suggest that in the future the dream may become a reality
Applications of enzyme biotechnology by Jeffery W Kelly( Book )

7 editions published in 1991 in English and held by 141 WorldCat member libraries worldwide

The Industry-University Cooperative Chemistry Program (IUCCP) has sponsored eight previous international symposia covering a range of topics of interest to industrial and academic chemists. The ninth IUCCP Symposium, held March 18-21, 1991 at Texas A & M University was the second in a two part series focusing on Biotechnology. The title for this Symposium "Applications of Enzyme Biotechnology" was by design a rather all encompassing title, similar in some respects to the discipline. Biotechnology refers to the application of biochemistry for the development of a commercial product. Persons employed in or interested in biotechnology may be chemists, molecular biologists, biophysicists, or physicians. The breadth of biotech research projects requires close collaboration between scientists of a variety of backgrounds, prejudices, and interests. Biotechnology is a comparatively new discipline closely tied to new developments in the fields of chemistry, biochemistry, molecular biology and medicine. The primary function of Texas A & M University is to educate students who will be appropriately trained to carry out the mission of biotechnology. The IUCCP Symposium serves as an important forum for fostering closer ties between academia and industry and exchanging ideas so important to this evolving area
Bioluminescence and chemiluminescence( Book )

in English and held by 5 WorldCat member libraries worldwide

Bioluminescence and chemiluminescence( Book )

in English and held by 3 WorldCat member libraries worldwide

Bioluminescence and chemiluminescence( Book )

2 editions published in 2000 in English and held by 3 WorldCat member libraries worldwide

Molecular chaperones by R. J Ellis( Book )

1 edition published in 1998 in English and held by 3 WorldCat member libraries worldwide

Currently one of the hottest topics in biochemistry, the concept of molecular chaperones has challenged the paradigm of protein self-assembly. Key figures in many disciplines review all aspects of molecular chaperones in this volume, which arises from a Royal Society discussion meeting. Overview chapters discuss the significance of chaperones in biochemistry, molecular genetics and cell biology. Each chapter is well referenced providing access to the literature
Bioluminescence and chemiluminescence( Book )

1 edition published in 1986 in English and held by 2 WorldCat member libraries worldwide

Bioluminescence and chemiluminescence( Book )

1 edition published in 1978 in English and held by 2 WorldCat member libraries worldwide

Methods in enzymology( Book )

1 edition published in 2005 in English and held by 1 WorldCat member library worldwide

Methods in enzymology( Book )

1 edition published in 2005 in English and held by 1 WorldCat member library worldwide

Luminescence-Based Biosensor Systems( Book )

2 editions published in 1997 in English and held by 1 WorldCat member library worldwide

Progress has been made in two related areas during the period of this grant. In the area of luminescence-based biosensor systems, we have developed sensitive methods to detect antibiotics in biological materials and foods using bioluminescence. We believe that our methods can be automated and applied to the rapid detection of antibiotics in biological fluids, food sources, and other materials. In related studies, the crystal structure of bacterial luciferase has been determined at 2.4 A resolution. This accomplishment represents a major step forward in our effort to understand this enzyme and how it works, including the details of its folding. Knowledge of the structure is crucial also to efforts to derivatize the enzyme for development of new generation biosensor systems
Documentation of the need and desirability of a Doctor of Arts in the physical sciences at S.I.U.E. by Thomas O Baldwin( Book )

1 edition published in 1971 in English and held by 1 WorldCat member library worldwide

Structural studies on bullfrog hemoglobin by Thomas O Baldwin( Book )

1 edition published in 1971 in English and held by 1 WorldCat member library worldwide

Biochemistry of bacterial bioluminescence( )

1 edition published in 1981 in English and held by 1 WorldCat member library worldwide

Applications of enzyme biotechnology : 9th Annual symposium : Papers( Book )

1 edition published in 1991 in English and held by 1 WorldCat member library worldwide

Structural and Functional Studies of Bioluminescent Proteins (an AASERT Grant)( )

1 edition published in 1997 in English and held by 0 WorldCat member libraries worldwide

This grant provided support between September 1993 and August 1996 for the dissertation research of several predoctoral students. Highlights of their collective accomplishments include: (a) participating in the crystallization and analysis of the high resolution structures of the bacterial luciferase Alpha Beta heterodimer and the Beta2 homodimer, (b) elucidation of a detailed kinetic mechanism for the folding and assembly of the luciferase subunits, (c) use of spectroscopic techniques and mutant enzymes to probe the active site and subunit interface of bacterial luciferase, and (d) characterization by genetic methods of the role of the LuxR transcriptional activator protein in density-dependent control of gene expression
Bacterial Luciferase: Determination of the Structure by X-Ray Diffraction( )

1 edition published in 1994 in English and held by 0 WorldCat member libraries worldwide

This project was focused on determination of the three-dimensional structure of bacterial luciferase. The structure of the enzyme is of fundamental importance to the understanding of the catalytic mechanism and the mode of interaction of the enzyme with accessory proteins, and is essential to future plans to develop biosensor technologies. In the course of this project, numerous crystallization trials were carried out and conditions were refined that permitted high resolution data to be collected and interpreted. In collaboration with Dr. Ivan Rayment of the University of Wisconsin, data have been collected from native crystals and 3 derivatives at 2.8 A. Higher resolution data are being collected at this time, and we fully expect to have a high resolution structure within the next few months, certainly by the end of the calendar year 1994. We have also developed crystallization protocols for several mutant luciferases. Structural analysis of the mutant luciferases should enable us to locate the active site in the three-dimensional structure of the wild-type enzyme, permit mechanistic interpretation of numerous experiments that have been reported over the past ca. 25 years, and assist us in designing the next generation of mutant enzymes to test hypotheses regarding the mechanism of light production by this intriguing and important enzyme
Bioluminescence and Chemiluminescence, Part C by Miriam M Ziegler( )

1 edition published in 2000 in English and held by 0 WorldCat member libraries worldwide

Since the publication of Bioluminescence and Chemiluminescence, Part B, genes have been cloned that encode luciferases from an array of bioluminescent organisms, novel applications of these genes have been developed, and much has been learned of the fundamental chemistry, biochemistry, structural biology, and biophysics of these intriguing enzymes. New strategies for application of chemiluminescence technology have been developed and refined, promising to further reduce the need to use radioisotopes in basic research and clinical laboratory settings. Methods for detection of low levels of ligh
 
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Molecular chaperonesMolecular chaperones
Alternative Names
Baldwin, Thomas Oakley.

Languages
English (74)

Covers
Bioluminescence and chemiluminescenceChemical aspects of enzyme biotechnology : fundamentalsApplications of enzyme biotechnologyBioluminescence and chemiluminescenceBioluminescence and chemiluminescenceMolecular chaperonesApplications of enzyme biotechnology : 9th Annual symposium : Papers