WorldCat Identities

Steitz, Thomas A.

Overview
Works: 11 works in 17 publications in 1 language and 292 library holdings
Genres: Biography 
Roles: Speaker
Classifications: QP624.75.P74, 574.87328
Publication Timeline
Key
Publications about  Thomas A Steitz Publications about Thomas A Steitz
Publications by  Thomas A Steitz Publications by Thomas A Steitz
Most widely held works by Thomas A Steitz
Structural studies of protein-nucleic acid interaction : the sources of sequence-specific binding by Thomas A Steitz ( Book )
6 editions published between 1990 and 1993 in English and held by 211 WorldCat member libraries worldwide
RNA polymerases as molecular motors ( )
2 editions published in 2009 in English and held by 48 WorldCat member libraries worldwide
This book, written by expert scientists in the field, analyses how diverse fields of scientific research interact on a specific example - RNA polymerases, The cell can be viewed as a 'collection of protein machines' and understanding these molecular machines requires sophisticated cooperation between cell biologists, geneticists, enzymologists, crystallographers, chemists and physicists. To observe these machines in action, researchers have developed entirely new methodologies for the detection and the nanomanipulation of single molecules. This book, written by expert scientists in the field, analyses how these diverse fields of research interact on a specific example - RNA polymerase. The book concentrates on RNA polymerases because they play a central role among all the other machines operating in the cell and are the target of a wide range of regulatory mechanisms. They have also been the subject of spectacular advances in their structural understanding in recent years, as testified by the attribution of the Nobel prize in chemistry in 2006 to Roger Kornberg. The book focuses on two aspects of the transcription cycle that have been more intensively studied thanks to this increased scientific cooperation - the recognition of the promoter by the enzyme, and the achievement of consecutive translocation steps during elongation of the RNA product. Each of these two topics is introduced by an overview, and is then presented by worldwide experts in the field, taking the viewpoint of their speciality. The overview chapters focus on the mechanism-structure interface and the structure-machine interface while the individual chapters within each section concentrate more specifically on particular processes-kinetic analysis, single-molecule spectroscopy, and termination of transcription, amongst others. Specific attention has been paid to the newcomers in the field, with careful descriptions of new emerging techniques and the constitution of an atlas of three-dimensional pictures of the enzymes involved. For more than thirty years, the study of RNA polymerases has benefited from intense cooperation between the scientific partners involved in the various fields listed above. It is hoped that a collection of essays from outstanding scientists on this subject will catalyse the convergence of scientific efforts in this field, as well as contribute to better teaching at advanced levels in Universities
The structural basis for how the large ribosomal subunit catalyses peptide bond formation by Thomas A Steitz ( )
1 edition published in 2008 in English and held by 18 WorldCat member libraries worldwide
Audio-visual presentation: Overview of protein synthesis by the ribosome -- Nature of the polypeptide exit tunnel in the large subunit -- The ribosome is a ribozyme -- Substrate induced fit at the peptidyl transferase center -- Proton shuttle mechanism and transition state stabilization -- Substrate interactions at the large subunit E-site -- Movie of the peptidyl transferase reaction
Nobel minds 2009 ( Visual )
1 edition published in 2010 in English and held by 7 WorldCat member libraries worldwide
Host introduces several topics for discussion including United States President, Barack Obama receiveing the Noble Peace Prize, global warming/integrity of science, and practical applications of their discoveries
Protein-nucleic acid interactions ( Book )
1 edition published in 1998 in English and held by 2 WorldCat member libraries worldwide
Crystal Structures of Three Misacylating Mutants of Escherichia coli Glutaminyl-tRNA Synthetase Complexed with tRNA(Gln) and ATP by John George Arnež ( )
1 edition published in 1996 in English and held by 1 WorldCat member library worldwide
The structural basis for how the large ribosomal subunit catalyses peptide bond formation by Thomas A Steitz ( )
1 edition published in 2008 in English and held by 1 WorldCat member library worldwide
Audio-visual presentation: Overview of protein synthesis by the ribosome -- Nature of the polypeptide exit tunnel in the large subunit -- The ribosome is a ribozyme -- Substrate induced fit at the peptidyl transferase center -- Proton shuttle mechanism and transition state stabilization -- Substrate interactions at the large subunit E-site -- Movie of the peptidyl transferase reaction
The structural basis for how the large ribosomal subunit catalyses peptide bond formation by Thomas A Steitz ( )
1 edition published in 2008 in English and held by 1 WorldCat member library worldwide
Audio-visual presentation: Overview of protein synthesis by the ribosome -- Nature of the polypeptide exit tunnel in the large subunit -- The ribosome is a ribozyme -- Substrate induced fit at the peptidyl transferase center -- Proton shuttle mechanism and transition state stabilization -- Substrate interactions at the large subunit E-site -- Movie of the peptidyl transferase reaction
DNA polymerase I: from crystal structure to function via genetics by Catherine Joyce ( Book )
1 edition published in 1987 in English and held by 1 WorldCat member library worldwide
Commencement ceremony (2010) including honorary degree recipient Abigail Disney by Lawrence University ( Visual )
1 edition published in 2010 in English and held by 1 WorldCat member library worldwide
 
moreShow More Titles
fewerShow Fewer Titles
Audience Level
0
Audience Level
1
  Kids General Special  
Audience level: 0.66 (from 0.00 for Crystal st ... to 0.92 for Protein-nu ...)
Alternative Names
Steitz, Thomas Arthur 1940-
Languages
English (17)
Covers