WorldCat Identities

Landweber, Laura F. (Laura Faye) 1967-

Overview
Works: 10 works in 36 publications in 1 language and 856 library holdings
Genres: Conference proceedings 
Roles: Author, Editor
Classifications: QH75, 576.58
Publication Timeline
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Most widely held works by Laura F Landweber
Genetics and the extinction of species : DNA and the conservation of biodiversity( Book )

7 editions published in 1999 in English and held by 540 WorldCat member libraries worldwide

In this collectiona̧ team of leading biologists demonstrates why the burgeoning field of conservation biology must continue to rely on the insights of population genetics if we to are preserve the diversity of living species
Evolution as computation : DIMACS workshop, Princeton, January 1999 by Laura F Landweber( Book )

14 editions published between 2000 and 2013 in English and held by 145 WorldCat member libraries worldwide

The study of the genetic basis for evolution has flourished in this century, as well as our understanding of the evolvability and programmability of biological systems. Genetic algorithms meanwhile grew out of the realization that a computer program could use the biologically-inspired processes of mutation, recombination, and selection to solve hard optimization problems. Genetic and evolutionary programming provide further approaches to a wide variety of computational problems. A synthesis of these experiences reveals fundamental insights into both the computational nature of biological evolution and processes of importance to computer science. Topics include biological models of nucleic acid information processing and genome evolution; molecules, cells, and metabolic circuits that compute logical relationships; the origin and evolution of the genetic code; and the interface with genetic algorithms, genetic and evolutionary programming. This research combines theory and experiments to understand the computations that take place in cells and the combinatorial processes that drive evolution at the molecular level
DNA based computers II : DIMACS workshop, June 10-12, 1996 by Annual Workshop on DNA based computers( Book )

7 editions published between 1990 and 1999 in English and held by 132 WorldCat member libraries worldwide

RNA editing and the evolution of mitochondrial DNA in kinetoplastid protozoa by Laura F Landweber( )

1 edition published in 1993 in English and held by 4 WorldCat member libraries worldwide

DIMACS workshop : June 10-12, 1996; [papers from the Second DIMACS Workshop on DNA Based Computers; at Princeton University, Princeton, N.J.]( Book )

1 edition published in 1999 in English and held by 2 WorldCat member libraries worldwide

DNA Based Computers : DIMACS Workshop, II : Proceedings( Book )

1 edition published in 1999 in English and held by 1 WorldCat member library worldwide

RNA-mediated epigenetic inheritance in oxytricha by Laura F Landweber( Visual )

1 edition published in 2009 in English and held by 1 WorldCat member library worldwide

"RNA, normally thought of as a conduit in gene expression, displays a novel mode of action inciliates, where RNA molecules provide both an organizing role in DNA rearrangements and a template that can transmit somatic substitutions to the next generation (Nowacki et al. 2008. Nature 451, 153-158). The opportunity for RNA-guided DNA repair is profound in Oxytricha, which destroys 95% of its germline genome through a process that severely fragments its chromosomes and then sorts and reorders the hundreds of thousands of tiny pieces remaining. Information for reordering comes from transiently-expressed maternal non-coding RNAs. A complete RNA cache of the maternal somatic genome may be available at a specific stage during development to provide a template for DNA rearrangement and to transmit heritable information."--Abstract
Molecular Computation With Automated Microfluidic Sensors (MCAMS)( )

1 edition published in 2004 in English and held by 0 WorldCat member libraries worldwide

We combined microfluidic technology with recently developed algorithms of nucleic acid-based computing to demonstrate a compact, automated nucleotide-based computational device capable of rapid detection of computational output. We explored both experimental and theoretical aspects of the construction of microfluidic nucleic acid computing. Microreactors implementing Boolean operators lent themselves to a relatively simple implementation of DNA computing. On the theoretical side, we simulated the performance of individual reactors and designed small reactor systems (sorters) mimicking AND and OR gates and systems capable of solving complex Boolean expressions. We compared positive vs. negative selection and parallel vs. series arrangements of reactors, considering both the accuracy of and disproportionate representation (bias) within the final pool of solutions. We also developed O(P2) software that designs operating instructions for an O(NL) system capable of solving any Boolean expression. We developed software for automated data collection and signal analysis of electronic detection of labeled DNA and explored novel nanocrystal probes that enable detection of DNA for readout in on-chip electrical assays. We focused in the areas of methods to produce nanocrystals bearing precise numbers of oligonucleotides, and development of nanocrystal precise groupings that bear a collective signature
 
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Alternative Names
Landweber, Laura

Languages
English (36)

Covers
Evolution as computation : DIMACS workshop, Princeton, January 1999DNA based computers II : DIMACS workshop, June 10-12, 1996DNA based computers II : DIMACS workshop, June 10-12, 1996 ; [papers from the Second DIMACS Workshop on DNA Based Computers ; at Princeton University, Princeton, N.J.]. Laura F. Landweber, Eric B. Baum, edDIMACS workshop : June 10-12, 1996; [papers from the Second DIMACS Workshop on DNA Based Computers; at Princeton University, Princeton, N.J.]DNA Based Computers : DIMACS Workshop, II : Proceedings