WorldCat Identities

Holt, Patrick G.

Overview
Works: 17 works in 22 publications in 1 language and 28 library holdings
Genres: Academic theses 
Roles: Contributor, Editor, Other, Author
Classifications: RC585, 616.97
Publication Timeline
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Most widely held works by Patrick G Holt
Allergy and allergic diseases( )

3 editions published between 2008 and 2009 in English and held by 5 WorldCat member libraries worldwide

This two volume book is an outstanding reference source on all aspects of allergy and allergic diseases. Covering virtually every allergic condition, from the immunological and molecular basis of the allergic response to future trends in allergic disease prevention, this new international editorial team (A.B. Kay, Jean Bousquet, Pat Holt and Allen Kaplan) have completely revised and updated the text, from both a scientific and clinical perspective. References will continue to be added to the text until it goes to press making this the most up-to-date book available in the field. This second edition consists of more than 1,800 pages contained within 98 chapters
Allergy and allergic diseases by A. B Kay( Book )

4 editions published between 2008 and 2009 in English and held by 3 WorldCat member libraries worldwide

Reserve your copy now This two volume book is an outstanding reference source on all aspects of allergy and allergic diseases. Covering virtually every allergic condition, from the immunological and molecular basis of the allergic response to future trends in allergic disease prevention, this new international editorial team (A.B. Kay, Jean Bousquet, Pat Holt and Allen Kaplan) have completely revised and updated the text, from both a scientific and clinical perspective. References will continue to be added to the text until it goes to press making this the most up-to-date book available in the field. This second edition consists of more than 1,800 pages contained within 98 chapters. The price includes a fully searchable companion CD ROM with the complete text and over 300 images from the book in full colour
Allergy and allergic diseases by A. B Kay( )

1 edition published in 2009 in English and held by 2 WorldCat member libraries worldwide

The pattern of methacholine responsiveness in mice is dependent on antigen challenge dose by Graeme R Zosky( )

1 edition published in 2004 in English and held by 2 WorldCat member libraries worldwide

Meta-analysis identifies seven susceptibility loci involved in the atopic march by Ingo Marenholz( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Risk factors and prognosis of recurrent wheezing in Chinese young children: a prospective cohort study by Jing Guo( )

1 edition published in 2019 in English and held by 2 WorldCat member libraries worldwide

Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses by Niamh M Troy( )

1 edition published in 2016 in English and held by 2 WorldCat member libraries worldwide

Persistent activation of interlinked type 2 airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic asthmatics by Anya C Jones( )

1 edition published in 2018 in English and held by 2 WorldCat member libraries worldwide

Studies on the mechanism of induction of tyrosine aminotransferase in neonatal rat liver by Patrick G Holt( )

1 edition published in 1970 in English and held by 1 WorldCat member library worldwide

After asthma: redefining airways diseases( )

1 edition published in 2018 in English and held by 1 WorldCat member library worldwide

Anti-infective proteins in breast milk and asthma-associated phenotypes during early childhood( )

1 edition published in 2014 in English and held by 1 WorldCat member library worldwide

Abstract Background The impact of breast milk feeding on susceptibility to asthma in childhood is highly controversial, due in part to failure of the majority of studies in the area to adequately account for key confounders exemplified by respiratory infection history, plus the effects of recall bias. Methods As part of a prospective cohort study on the role of respiratory infections in asthma development in high-risk children, we measured the concentration of a panel of anti-infective proteins in maternal milk samples and analyzed associations between these and subsequent atopy-, infection-, and asthma-related outcomes prospectively to age 10 years. Results We observed significant but transient inverse associations between the concentration of milk proteins and susceptibility to upper respiratory infections in year 1 only, and parallel but positive transient associations with early lower respiratory infections and atopy. No associations were seen with asthma-related outcomes. Conclusions Breast milk feeding may influence the expression of inflammatory symptoms associated with respiratory infections and atopy in early life, but these effects appear to be inconsistent and transient. The heterogeneous nature of breast-feeding effects suggests it may influence systemic immunoinflammatory function at several different levels
Allergy and allergic diseases by A. B Kay( Book )

1 edition published in 2008 in English and held by 1 WorldCat member library worldwide

More than 100 chapters written by world leading authorities on allergy make this the most comprehensive textbook available. It is suitable for GPs but is detailed and will be of great value to allergologists and immunologists
Prevention - what is the most promising approach?( )

1 edition published in 2014 in English and held by 1 WorldCat member library worldwide

Functional differences in airway dendritic cells determine susceptibility to IgE-sensitization( )

1 edition published in 2018 in English and held by 1 WorldCat member library worldwide

Abstract: Respiratory IgE-sensitization to innocuous antigens increases the risk for developing diseases such as allergic asthma. Dendritic cells (DC) residing in the airways orchestrate the immune response following antigen exposure and their ability to sample and present antigens to naïve T cells in airway draining lymph nodes contributes to allergen-specific IgE-sensitization. In order to characterize inhaled antigen capture and presentation by DC subtypes in vivo, we used an adjuvant-free respiratory sensitization model using two genetically distinct rat strains, one of which is naturally resistant and the other naturally susceptible to allergic sensitization. Upon multiple exposures to ovalbumin (OVA), the susceptible strain developed OVA-specific IgE and airway inflammation, whereas the resistant strain did not. Using fluorescently tagged OVA and flow cytometry, we demonstrated significant differences in antigen uptake efficiency and presentation associated with either IgE-sensitization or resistance to allergen exposures in respective strains. We further identified CD4 + conventional DC (cDC) as the subset involved in airway antigen sampling in both strains, however, CD4 + cDC in the susceptible strain were less efficient in OVA sampling and displayed increased MHC-II expression compared with the resistant strain. This was associated with generation of an exaggerated Th2 response and a deficiency of airway regulatory T cells in the susceptible strain. These data suggest that subsets of cDC are able to induce either sensitization or resistance to inhaled antigens as determined by genetic background, which may provide an underlying basis for genetically determined susceptibility to respiratory allergic sensitization and IgE production in susceptible individuals. Abstract : By comparing two rat strains with different susceptibility to respiratory sensitization, we identify that antigen-specific IgE sensitization is associated with deficient antigen sampling by CD4 + conventional dendritic cells in the airways and a deficient migration of CD4 + regulatory T cells to the airways. Together, these data highlight the critical steps involved in the process of respiratory IgE sensitisation
Regulation of immune and inflammatory responses in the respiratory tract by Patrick G Holt( )

1 edition published in 1988 in English and held by 1 WorldCat member library worldwide

Allergy and allergic diseases( Book )

1 edition published in 2008 in English and held by 1 WorldCat member library worldwide

Serum modulation ofin vitro cellular immune reactivity to Epstein-Barr virus-associated antigen by Patrick G Holt( )

1 edition published in 1976 in English and held by 0 WorldCat member libraries worldwide

 
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Audience level: 0.83 (from 0.40 for Studies on ... to 1.00 for Serum modu ...)

WorldCat IdentitiesRelated Identities
Allergy and allergic diseases Allergy and allergic diseases Allergy and allergic diseases Allergy and allergic diseases
Covers
Allergy and allergic diseasesAllergy and allergic diseasesAllergy and allergic diseases
Alternative Names
Patrick G. Holt australischer Mediziner

Patrick G. Holt dochtúir Astrálach

Patrick G. Holt investigador australianu

Patrick G. Holt médecin australien

Patrick G. Holt médico australiano

Patrick G. Holt metge australià

Patrick G. Holt mjek australian

Patrick G. Holt onderzoeker uit Australië

باتريك ج. هولت طبيب أسترالي

Languages
English (22)