WorldCat Identities

United States Department of Energy Office of Science

Overview
Works: 3,920 works in 3,990 publications in 1 language and 25,674 library holdings
Genres: Conference proceedings  Periodicals 
Roles: Sponsor, Researcher, Creator
Classifications: QH324.2, 572.8629072
Publication Timeline
Key
Publications about United States Publications about United States
Publications by United States Publications by United States
Most widely held works about United States
 
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Most widely held works by United States
Genomics and its impact on science and society the Human Genome Project and beyond ( )
3 editions published between 2007 and 2008 in English and held by 330 WorldCat member libraries worldwide
Maintaining U.S. preeminence in science university support ( )
1 edition published in 2006 in English and held by 234 WorldCat member libraries worldwide
The challenge and promise of scientific computing ( )
1 edition published in 2003 in English and held by 226 WorldCat member libraries worldwide
Using nature's own toolkit to clean up the environment ( )
1 edition published in 2006 in English and held by 225 WorldCat member libraries worldwide
The beauty of nanoscale science ( )
1 edition published in 2003 in English and held by 225 WorldCat member libraries worldwide
Dark energy the mystery that dominates the universe ( )
1 edition published in 2003 in English and held by 224 WorldCat member libraries worldwide
Systems biology knowledgebase for a new era in biology by Genomics:GTL Systems Biology Knowledgebase Workshop ( )
2 editions published in 2009 in English and held by 224 WorldCat member libraries worldwide
"Biology has entered a systems-science era with the goal to establish a predictive understanding of the mechanisms of cellular function and the interactions of biological systems with their environment and with each other. Vast amounts of data on the composition, physiology, and function of complex biological systems and their natural environments are emerging from new analytical technologies. Effectively exploiting these data requires developing a new generation of capabilities for analyzing and managing the information. By revealing the core principles and processes conserved in collective genomes across all biology and by enabling insights into the interplay between an organism's genotype and its environment, systems biology will allow scientific breakthroughs in our ability to project behaviors of natural systems and to manipulate and engineer managed systems. These breakthroughs will benefit Department of Energy (DOE) missions in energy security, climate protection, and environmental remediation. To promote development of a data and information management system, or knowledgebase, DOE's Office of Biological and Environmental Research (OBER) hosted a workshop May 28-30, 2008, in Washington, D.C. Experts from scientific disciplines relevant to DOE missions and from the enabling technologies (e.g., bioinformatics, computer science, database development, and systems architecture) met to determine the opportunities and requirements for developing and managing this knowledgebase for OBER's Genomics:GTL program (GTL). Workshop participants defined the proposed GTL knowledgebase, or GKB, as an informatics resource that would focus on DOE science-application areas yet also be widely and easily applicable to all systems biology research. Also discussed were requirements for effective development of data capabilities for systems biology that could be applied specifically to plants and microbes (i.e., bacteria, archaea, fungi, and protists--unicellular eukaryotes such as microalgae) as well as to three areas of science related to DOE missions: (1) researching and developing biofuels, (2) advancing fundamental understanding of the global carbon cycle, and (3) understanding and using biological systems for environmental remediation. Participants were organized into working groups based on four knowledgebase themes: data, metadata, and information; data integration; database architecture and infrastructure; and community and user issues. The workshop highlighted DOE's unique and extensive data-management needs as a foundation of mission-inspired systems biology research. These needs require a principal GTL data resource, the GKB, with critical links to complementary systems supported by other agencies and community organizations worldwide. This knowledgebase would facilitate a new level of scientific inquiry by serving as a central component for the integration of modeling, simulation, experimentation, and bioinformatic approaches. The GKB also would be a primary resource for data sharing and information exchange among the GTL community. Furthermore, not only would the GKB allow scientists to expand, compute, and integrate data and information program wide, it also would drive two classes of work: experimental design and modeling and simulation. Integrating data derived from computational predictions and modeling, as envisioned in the knowledgebase project, would increase data completeness, fidelity, and accuracy. These advancements in turn would greatly improve modeling and simulation, leading to new experimentation, analyses, and mechanistic insight. Scientists' ever-increasing exploitation of the dynamic linkages among data integration, experimentation, and modeling and simulation--aided by the GKB--will advance efforts to achieve a predictive understanding of the functions of biological systems. The knowledgebase, therefore, must serve multiple roles, including (1) a repository of data and results from high-throughput experiments; (2) a collection of tools to derive new insights through data synthesis, analysis, and comparison; (3) a framework to test scientific understanding; (4) a heuristic capability to improve the value and sophistication of further inquiry; and (5) a foundation for prediction, design, manipulation, and, ultimately, engineering of biological systems to meet national needs in bioenergy, environmental remediation, and carbon cycling."--Executive summary
Fusion energy bringing a star to Earth ( )
2 editions published in 2003 in English and held by 223 WorldCat member libraries worldwide
Biotechnology for Energy Security ( )
1 edition published in 2003 in English and held by 222 WorldCat member libraries worldwide
Building a 21st century workforce ( )
1 edition published in 2003 in English and held by 220 WorldCat member libraries worldwide
Carbon cycling and biosequestration integrating biology and climate through systems science : report from the March 2008 workshop ( )
1 edition published in 2008 in English and held by 216 WorldCat member libraries worldwide
U.S. Department of Energy, Office of Science ( )
2 editions published in 2009 in English and held by 214 WorldCat member libraries worldwide
Systems biology knowledgebase for a new era in biology executive summary ( )
1 edition published in 2009 in English and held by 214 WorldCat member libraries worldwide
Carbon sequestration research and development ( Book )
2 editions published in 1999 in English and held by 214 WorldCat member libraries worldwide
Research Priorities for Tropical Ecosystems Under Climate Change Workshop report by Research Priorities for Tropical Ecosystems Under Climate Change Workshop ( )
2 editions published in 2012 in English and held by 206 WorldCat member libraries worldwide
CRD report by Lawrence Berkeley National Laboratory ( )
in English and held by 194 WorldCat member libraries worldwide
NERSC news by National Energy Research Scientific Computing Center (U.S.) ( )
in English and held by 192 WorldCat member libraries worldwide
New frontiers in characterizing biological systems report from the May 2009 workshop ( )
3 editions published between 2009 and 2010 in English and held by 190 WorldCat member libraries worldwide
"To promote development of a new generation of characterization technologies, BER hosted the workshop, New Frontiers in Characterizing Biological Systems, in May 2009. Experts from scientific disciplines relevant to DOE missions and from the enabling technologies (e.g., optical spectroscopy, genomic sequencing technology, electrochemistry, electron microscopy, and mass spectrometry) met to determine the opportunities and requirements for identifying and developing new tools and analytical approaches for characterizing cellular- and multicellularlevel functions and processes that are essential to develop solutions for DOE missions in biofuels, carbon cycling and biosequestration, low dose radiation, and environmental stewardship. The intent of the workshop was to broadly explore future technology capabilities that are needed, not current technologies and their development"--P. 2 of cover
Communicating the future best practices for communication of science and technology to the public : conference proceedings, March 6-8, 2002 by Best Practices for Communication of Science and Technology to the Public ( Book )
2 editions published in 2002 in English and held by 178 WorldCat member libraries worldwide
 
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Languages
English (76)
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