WorldCat Identities

Greider, Carol W.

Overview
Works: 13 works in 24 publications in 3 languages and 370 library holdings
Genres: Conference papers and proceedings  Biography  Textbooks 
Roles: Editor, Author, Other
Classifications: QH600.3,
Publication Timeline
.
Most widely held works about Carol W Greider
 
Most widely held works by Carol W Greider
Telomeres( Book )

9 editions published in 1995 in English and held by 294 WorldCat member libraries worldwide

Chapters in this volume cover telomere structure and function in a range of organisms, focusing on how they are maintained, their roles in cell division and gene expression, and how deficiencies in these structures contribute to cancers and other diseases and even aging
Abstracts of papers presented at the 1999 meeting on telomeres & telomerase, March 25-March 28, 1999( Book )

1 edition published in 1999 in English and held by 16 WorldCat member libraries worldwide

Abstracts of papers presented at the 2001 meeting on telomeres & telomerase, March 28-April 1, 2001( Book )

1 edition published in 2001 in English and held by 14 WorldCat member libraries worldwide

Molecular biology : principles of genome function by Nancy Lynn Craig( Book )

3 editions published between 2010 and 2014 in English and held by 13 WorldCat member libraries worldwide

Molecular Biology: Principles of Genome Function offers a fresh, distinctive approach to the teaching of molecular biology. With its focus on key principles, its emphasis on the commonalities that exist between the three kingdoms of life, and its integrated approach throughout, it is the perfect companion to any molecular biology course
Abstracts of papers presented at the 2003 meeting on telomeres & telomerase, April 30-May 4, 2003( Book )

1 edition published in 2003 in English and held by 6 WorldCat member libraries worldwide

Nobel minds 2009( Visual )

1 edition published in 2010 in English and held by 5 WorldCat member libraries worldwide

Host introduces several topics for discussion including United States President, Barack Obama receiveing the Noble Peace Prize, global warming/integrity of science, and practical applications of their discoveries
Identification and characterization of telomere terminal transferase by Carol W Greider( )

1 edition published in 1987 in English and held by 3 WorldCat member libraries worldwide

Tetrahymena cell extracts were shown to contain an enzyme activity which synthesizes repeats of the telomeric DNA sequence TTGGGG, de novo onto appropriate telomeric DNA primers. This telomere terminal transferase (telomerase) activity was independent of template DNA and was not inhibited by the drug aphidicolin, a known potent inhibitor of $\alpha$-type DNA polymerases. Different synthetic oligonucleotides containing the G-rich strand telomeric sequences from Tetrahymena, Oxytricha, yeast, trypanosomes and Dictyostelium all primed the addition of TTGGGG repeats in vitro. C-rich strand telomeric oligonucleotides and non-telomeric oligonucleotides did not prime the TTGGGG repeat addition. These results implied that primer recognition by the telomerase involves both specific structural aspects of the G-rich oligonucleotides In addition, the 3$\sp\prime$end sequence of the primers was shown to specify which nucleotides were added first in the reaction
Telomeros, telomerasa y cancer by Carol W Greider( )

2 editions published in 1996 in Spanish and held by 2 WorldCat member libraries worldwide

Telomerase and the consequences of telomere dysfunction by Carol W Greider( Visual )

1 edition published in 2010 in English and held by 1 WorldCat member library worldwide

(CIT): Telomeres protect chromosome ends from being recognized as DNA damage and chromosomal rearrangements. Conventional replication leads to telomere shortening, but telomere length is maintained by the enzyme telomerase that synthesizes telomere sequences de novo onto chromosome ends. Telomerase is specialized reverse transcriptase, requiring both a catalytic protein and an essential RNA component. In the absence of telomerase, telomeres shorten progressively as cells divide, and telomere function is lost. For this reason, telomerase is required for cells that undergo many rounds of divisions, especially tumor cells and some stem cells. The Greider lab is focused understanding telomerase and cellular and organismal consequences of telomere dysfunction. We use biochemistry, yeast and mice to examine telomere function. We generated telomerase null mice that are viable and show progressive telomere shortening for up to six generations. In the later generations, when telomeres are short, cells die via apoptosis or senescence. Crosses of these telomerase null mice to other tumor prone mice show that tumor formation can be greatly reduced by short telomeres. We also are using our telomerase null mice to explore the role of telomerase stem cells and aging. In human families, Telomerase mutations cause autosomal dominant dyskeratosis congenita and the associated bone marrow failure. We have developed a strain of mice that are haploinsufficient for telomerase and show many hallmarks of dyskeratosis congenita and age related degenerative disease. Our lab is focused on understanding how short telomeres cause these diseases as well as the mechanisms that regulate telomere length equilibrium. Lecture Objectives: 1. Understand the role of telomerase in telomere length 2. Understand the effect of short telomeres in cancer cell growth 3. Discuss role of telomere shortening in age related disease
Telomerase and the consequences of telomere dysfunction( Visual )

1 edition published in 2003 in English and held by 1 WorldCat member library worldwide

(Producer) Dr. Greider discusses her recent research on the cellular consequences of loss of telomere function. Using mouse and yeast models the Greider laboratory is exploring the mechanisms that initiate genomic instability and the consequences of that instability for tumor formation
Duan li by lai ke ben Bu( Book )

1 edition published in 2002 in Chinese and held by 1 WorldCat member library worldwide

 
moreShow More Titles
fewerShow Fewer Titles
Audience Level
0
Audience Level
1
  Kids General Special  
Audience level: 0.61 (from 0.04 for Molecular ... to 0.96 for Telomerase ...)

Molecular biology : principles of genome function
Alternative Names
Carol Greider Amerikaans moleculair bioloog

Carol Greider Amerikansk molekylärbiolog

Carol Greider bioquímica estadounidense

Carol Greiderová

Carol W. Greider

Carol W. Greider amerikai molekuláris biológus

Carol W. Greider biologa statunitense

Carol W. Greider US-amerikanische Molekularbiologin

Carol Widney Greider

Carola W. Greider

Carolyn Widney Carol Greider

Greider, Carolyn Widney

Грейдер, Кэрол

Керол Грейдер

Кэрал Грэйдэр

Кэрол Грейдер

קרול גריידר

كارول غريدر

کارول ڈبلیو. گریڈر

کارول گریدر

کیرل گرائیدر

कैरोल ग्रीडर

ক্যারল গ্রেইডার‌

ਕੈਰੋਲ ਗਰਾਈਡਰ

கரோல் கிரெய்டர்

കാരൾ ഗ്രെയ്ഡർ

캐럴 그라이더 미국 존스 홉킨스 대학교의 생물학 및 유전학과 교수로 재직중인 분자생물학자이다.

キャロル・W・グライダー

卡罗尔·格雷德

Languages
Covers