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Advances in Immunology: (Volume 87, Advances in Immunology)
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Advances in Immunology: (Volume 87, Advances in Immunology)

Author: Frederick W Alt; MyiLibrary.
Publisher: London Elsevier Science & Technology 2005.
Series: Advances in immunology, 87
Edition/Format: Book : Document : English
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Genre/Form: Electronic books.
Material Type: Document, Internet resource
Document Type: Book, Computer File, Internet Resource
All Authors / Contributors: Frederick W Alt; MyiLibrary.
ISBN: 6610633177 9786610633173
OCLC Number: 441761507
Notes: Title from e-book title screen (viewed August 16, 2007).
Description: 360 p.
Contents: Cover -- front cover -- copyright -- table of contents -- Contributors -- Role of the LAT Adaptor in T-Cell Development and Th2 Differentiation -- Abstract -- 1. Introduction -- 2. The LAT Signalosome -- 3. LAT: An Essential Component of the Pre-TCR -- 4. Role of LAT in ?d T-Cell Development -- 5. Negative Regulatory Role of LAT -- 6. Positive and Negative Selection in LatY136F Mice -- 7. Cooperative Assemblies Within the LAT Signalosome -- 8. Redundancy Among LAT Tyrosines -- 9. Mechanisms of Signal Termination by LAT -- 10. Th2-Type Immunity in LatY136F and LatY7/8/9F Mice -- 11. Is a LAT-Signalosome Pathology Taking Shape? -- 12. Concluding Remarks -- Acknowledgments -- References -- The Integration of Conventional and Unconventional T Cells that Characterizes Cell-Mediated Responses -- Abstract -- 1. Introduction -- 2. Integrating Immune Responses in the Public Good -- 3. Evidence for T-cell Integration -- 4. Mechanisms of Action of Unconventional T Cells -- 5. Immune Integration via Cytolysis by ?d Cells -- 6. Targeting by Cytolytic ?d Cells -- 7. Immunointegration by Cytokines -- 8. Immunointegration by Chemokines -- 9. Immunointegration by Adhesion and Costimulatory Molecules -- 10. Additional Clues to Immunoregulation -- 11. A Spectrum of Unconventional T Cells -- 12. Unconventional T Cells and NK Cells -- 13. A Developmental Program of T-Cell Integration -- 14. T-Cell Integration: Genetics and Disease -- Acknowledgments -- References -- Negative Regulation of Cytokine and TLR Signalings by SOCS and Others -- 1. Introduction -- 2. Cytokine Signaling -- 3. Negative Regulation of Cytokine Signaling -- 4. Regulation of Cytokine Signaling by SOCS Proteins (Tables 1 and 2) -- 5. TLR-Mediated Pathways -- 6. Signal Transduction Pathways Through TLRs -- 7. Major Biological Events by the TLR-Mediated Cell Activation -- 8. Pathophysiological Roles for TLR-Mediated Signal Pathways -- 9. Negative Regulation of the TLR Signalings -- 10. Regulation of TLR Signaling by SOCS -- 11. Concluding Remarks -- References -- Pathogenic T-Cell Clones in Autoimmune Diabetes: More Lessons from the NOD Mouse -- Abstract -- 1. Introduction -- 2. Pathogenic T-Cell Clones-Effector Function -- 3. Migration of Pathogenic T-Cell Clones -- 4. T-Cell Clones in T-Cell Receptor Transgenic (TCR-Tg) Mice -- 5. Antigens for Pathogenic T-Cell Clones -- 6. Tracking of Pathogenic T-Cell Clones with MHC Tetramers -- 7. Concluding Remarks -- References -- The Biology of Human Lymphoid Malignancies Revealed by Gene Expression Profiling -- Abstract -- 1. Introduction -- 2. Molecular Diagnosis of Lymphoid Malignancies -- 3. Gene Expression-Based Survival Predictors -- 4. Concluding Remarks -- References -- New Insights into Alternative Mechanisms of Immune Receptor Diversification -- Abstract -- 1. Introduction -- 2. Variation in Innate
Series Title: Advances in immunology, 87

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