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| Document Type: | Book |
|---|---|
| All Authors / Contributors: |
Jens Kurreck |
| ISBN: | 9780854041169 0854041168 |
| OCLC Number: | 237326966 |
| Description: | xvii, 343 p. : ill. (some col.) ; 24 cm. |
| Contents: | The role of backbone modifications in oligonucleotide-based strategies -- Genasense (G3139) : an antisense Bcl-2 oligodeoxyribonucleotide with substantial clinical activity and a complex mechanism of action -- Antisense morpholino oligomers and their peptide conjugates -- Peptide-peptide nucleic acid conjugates for modulation of gene expression -- Locked nucleic acid: properties and therapeutic aspects -- Immune stimulatory oligonucleotides -- Decoy oligodeoxynucleotides to treat inflammatory diseases -- AS1411 : development of an anticancer aptamer -- Spiegelmer NOX-E36 for renal diseases -- Strategies for the delivery of oligonucleotides in vivo -- Lipid-mediated in vivo delivery of small interfering RNAs -- Vector-mediated and viral delivery of short hairpin RNAs -- Development of an RNAi-based gene therapy against HIV-1 -- RNA based therapies for treatment of HIV infection. |
| Series Title: | RSC biomolecular sciences. |
| Responsibility: | edited by Jens Kurreck. |
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