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| Document Type: | Book |
|---|---|
| All Authors / Contributors: |
Paul Allan Bartlett; Michael Entzeroth; Royal Society of Chemistry (Great Britain) |
| ISBN: | 9780854048427 0854048421 |
| OCLC Number: | 63703046 |
| Description: | xxiv, 420 p. : col. ill. ; 24 cm. |
| Contents: | The use of polymer-assisted solution-phase synthesis and automation for the high-throughput preparation of biologically active compounds / Steven V. Ley, Mark Ladlow and Emma Vickerstaffe -- Accelerated chemistry : microwave, sonochemical, and fluorous phase techniques / Kristofer Olofsson, Peter Nilsson and Mats Larhed -- Biosynthesis of "unnatural" natural products / Yi Tang and Chaitan Khosla -- Combinatorial synthetic design : the balance of novelty and familiarity / A. Ganesan -- Compound collections : acquisition, annotation, and access / Reg Richardson -- Chemical diversity : definition and quantification / Alan C. Gibbs and Dimitris K. Agrafiotis -- Focused libraries : the evolution in strategy from large-diversity libraries to the focused library approach / Ruben Tommasi and Ivan Cornella -- Translating peptides into small molecules / Gerd Hummel, Ulrich Reineke and Ulf Reimer -- High-density plates, microarrays, microfluidics / Christof Fattinger and Gregor Dernick -- Fluorescence technologies for the investigation of chemical libraries / Eric Trinquet and Gérard Mathis -- The use of genetically engineered cell-based assays in in-vitro drug discovery / Renate Schnitzer and Wolfgang Sommergruber -- NMR-based screening : a powerful tool in fragment-based drug discovery / Jochen Klages, Murray Coles and Horst Kessler -- Screening chemical microarrays : methods and applications / Pappanaicken R. Kumaresan and Kit S. Lam -- Screen/counter-screen : early assessment of selectivity / Martyn N. Banks, Litao Zhang and John G. Houston -- Concepts for in vitro profiling : drug activity, selectivity and liability / Michael B. Bolger, Robert Fraczkiewicz, Michael Entzeroth and Boyd Steere -- In silico surrogates for in vivo properties : profiling for ADME and toxicological behavior / Michael B. Bolger, Robert Fraczkiewicz, Michael Entzeroth and Boyd Steere -- Uses of high content screening in chemical optimization / Francesca Casano, Zhuyin Li and Tina Garyantes. |
| Series Title: | RSC biomolecular sciences. |
| Responsibility: | edited by Paul A. Bartlett, Michael Entzeroth. |
| More information: |
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