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2-D PAGE map analysis : methods and protocols

Author: Emilio Marengo; Elisa Robotti
Publisher: New York, NY : Humana Press : Springer, ©2016.
Series: Methods in molecular biology (Clifton, N.J.), v. 1384.; Springer protocols (Series)
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Exploring the 2-D gel mapping field, the chapters in this book are separated into four different categories: Part I talks about 2-D maps reproducibility and maps modeling; Part II describes the image analysis tools that provide spot volume datasets; Part III is about the statistical methods applied to spot volume datasets to identify candidate biomarkers; and Part IV discusses differential analysis from direct image  Read more...
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Emilio Marengo; Elisa Robotti
ISBN: 9781493932559 1493932551 1493932543 9781493932542
OCLC Number: 930713761
Description: 1 online resource (xvi, 331 pages) : illustrations (some color).
Contents: Sources of experimental variation in 2-D maps : the importance of experimental design in gel-based proteomics / Cristina-Maria Valcu and Mihai Valcu --
Decoding 2-D maps by autocovariance function / Maria Chiara Pietrogrande, Nicola Marchetti, and Francesco Dondi --
Two-dimensional gel electrophoresis image analysis via dedicated software packages / Martin H. Maurer --
Comparative evaluation of software features and performances / Daniela Cecconi --
Image pretreatment tools I : algorithms for map denoising and background subtraction methods / Carlo Vittorio Cannistraci and Massimo Alessio --
Image pretreatment tools II : normalization techniques for 2-DE and 2-D DIGE / Elisa Robotti, Emilio Marengo, and Fabio Quasso --
Spot matching of 2-DE images using distance, intensity, and pattern information / Hua-Mei Xin and Yuemin Zhu --
Algorithms for warping of 2-D PAGE maps / Marcello Manfredi, Elisa Robotti, and Emilio Marengo --
2-DE gel analysis : the spot detection / Simona Martinotti and Elia Ranzato --
GENOCOP algorithm and hierarchical grid transformation for image warping of two-dimensional gel electrophoretic maps / Elisa Robotti, Emilio Marengo, and Marco Demartini --
Detection and quantification of protein spots by pinnacle / Jeffrey S. Morris and Howard B. Gutstein --
Novel gaussian extrapolation approach for 2-D gel electrophoresis saturated protein spots / Massimo Natale, Alfonso Caiazzo, and Elisa Ficarra --
Multiple testing and pattern recognition in 2-DE proteomics / Sebastien C. Carpentier --
Chemometric multivariate tools for candidate biomarker identification : LDA, PLS-DA, SIMCA, ranking-PCA / Elisa Robotti and Emilio Marengo --
Use of legendre and zernike moment functions for the comparison of 2-D PAGE maps / Emilio Marengo, Elisa Robotti, and Marco Demartini --
Nonlinear dimensionality reduction by minimum curvilinearity for unsupervised discovery of patterns in multidimensional proteomic data / Massimo Alessio and Carlo Vittorio Cannistraci --
Differential analysis of 2-D maps by pixel-based approaches / Emilio Marengo, Elisa Robotti, and Fabio Quasso.
Series Title: Methods in molecular biology (Clifton, N.J.), v. 1384.; Springer protocols (Series)
Other Titles: Two-D page map analysis
Responsibility: edited by Emilio Marengo and Elisa Robotti.

Abstract:

Exploring the 2-D gel mapping field, the chapters in this book are separated into four different categories: Part I talks about 2-D maps reproducibility and maps modeling;  Read more...

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