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Ability of polyvalent (Crotalidae) antivenom to neutralize local myonecrosis induced by Crotalus atrox venom.
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Ability of polyvalent (Crotalidae) antivenom to neutralize local myonecrosis induced by Crotalus atrox venom.

Author: CL Ownby; TR Colberg
Edition/Format: Article Article : English
Publication:Toxicon : official journal of the International Society on Toxinology, 1986; 24(2): 201-3
Database:From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
Summary:
Wyeth's polyvalent (Crotalidae) antivenom was tested in mice for its ability to neutralize local myonecrosis induced by crude Crotalus atrox venom. A light microscopic assay was used to quantitate myonecrosis after i.m. injection of antivenom-venom mixtures. The results indicate that antivenom neutralizes the local myotoxicity of up to 15 micrograms venom per g body weight of mice. This neutralization is  Read more...
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Details

Document Type: Article
All Authors / Contributors: CL Ownby; TR Colberg
ISSN:0041-0101
OCLC Number: 115635847
Language Note: English
Awards:

Abstract:

Wyeth's polyvalent (Crotalidae) antivenom was tested in mice for its ability to neutralize local myonecrosis induced by crude Crotalus atrox venom. A light microscopic assay was used to quantitate myonecrosis after i.m. injection of antivenom-venom mixtures. The results indicate that antivenom neutralizes the local myotoxicity of up to 15 micrograms venom per g body weight of mice. This neutralization is significantly better than that previously reported for Crotalus viridis viridis venom.

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