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| Document Type: | Article |
|---|---|
| All Authors / Contributors: | CL Ownby; TR Colberg |
| ISSN: | 0041-0101 |
| OCLC Number: | 115635847 |
| Language Note: | English |
| Awards: |
Abstract:
Wyeth's polyvalent (Crotalidae) antivenom was tested in mice for its ability to neutralize local myonecrosis induced by crude Crotalus atrox venom. A light microscopic assay was used to quantitate myonecrosis after i.m. injection of antivenom-venom mixtures. The results indicate that antivenom neutralizes the local myotoxicity of up to 15 micrograms venom per g body weight of mice. This neutralization is significantly better than that previously reported for Crotalus viridis viridis venom.
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