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Absorption and drug development : solubility, permeability, and charge state

Autor: Alex Avdeef
Editora: Hoboken, N.J. : John Wiley & Sons, ©2012.
Edição/Formato   e-book : Documento : InglêsVer todas as edições e formatos
Base de Dados:WorldCat
Resumo:
BExplains how to perform and analyze the results of the latest physicochemical methods/b/ With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorption. The book emphasizes oral absorption, explaining all the physicochemical methods used today to analyze drug  Ler mais...
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Detalhes

Gênero/Forma: Electronic books
Tipo de Material: Documento, Recurso Internet
Tipo de Documento: Recurso Internet, Arquivo de Computador
Todos os Autores / Contribuintes: Alex Avdeef
ISBN: 9781118285961 1118285964 9781621982265 1621982262 1280589345 9781280589348 9781118286036 1118286030
Número OCLC: 795742377
Descrição: 1 online resource (xli, 698 pages) : illustrations
Conteúdos: Introduction Transport model pKa determination --
Octanol-water partitioning --
Liposome-water partitioning --
Solubility --
Permeability --
Pampa --
Permeability Caco 2/MDCK --
Permeability blood brain barrier.
Responsabilidade: Alex Avdeef.
Mais informações:

Resumo:

Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly  Ler mais...

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