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The acute mammalian toxicity of rare earth nitrates and oxides

저자: David W Bruce; Bernard E Hietbrink; Kenneth P DuBois; USAF School of Aerospace Medicine.
출판사: Brooks Air Force Base, Texas : USAF School of Aerospace Medicine, Aerospace Medical Division (AFSC), 1963.
시리즈: Technical documentary report, SAM-TDR, 63-38.
판/형식:   도서 : 국가 정부 간행물 : 영어
데이터베이스:WorldCat
요약:
Results of acute toxicity studies on rare earth nitrates indicate that their acute toxicity is highly dependent on the route of administration. The nitrate salts were moderately toxic when given intraperitoneally to rats and mice and only slightly toxic when administered orally to rats. With the exception of the transition elements, for which the oral LD50 vales were greater than 5,000 mg/kg, the compounds exhibited  더 읽기…
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자료 유형: 정부 간행물, 국가 정부 간행물
문서 형식:
모든 저자 / 참여자: David W Bruce; Bernard E Hietbrink; Kenneth P DuBois; USAF School of Aerospace Medicine.
OCLC 번호: 733063038
메모: "August 1963."
설명: iii, 6 p. : tables ; 27 cm.
일련 제목: Technical documentary report, SAM-TDR, 63-38.
책임: David W. Bruce, Bernard E. Hietbrink, Kenneth P. DuBois.

초록:

Results of acute toxicity studies on rare earth nitrates indicate that their acute toxicity is highly dependent on the route of administration. The nitrate salts were moderately toxic when given intraperitoneally to rats and mice and only slightly toxic when administered orally to rats. With the exception of the transition elements, for which the oral LD50 vales were greater than 5,000 mg/kg, the compounds exhibited an increase in toxicity with increasing atomic weight. The light lanthanons are highly toxic to rats by the intravenous route. The nitrate salts of cerium, praseodymium, neodymium, and samarium were from 7 to 11 times more toxic to females than to male rats. Erbium nitrate, a heavy lanthanon, did not show the marked sex difference in toxicity to rats. Rats were able to tolerate 1,000 mg/kg of the rare earth oxides given orally or intraperitoneally.

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