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Adenosine : a key link between metabolism and brain activity Titelvorschau

Adenosine : a key link between metabolism and brain activity

Verfasser/in: Susan Masino; Detlev Boison
Verlag: New York, NY : Springer, ©2013.
Ausgabe/Format   E-Book : Dokument : EnglischAlle Ausgaben und Formate anzeigen
Homeostasis of key metabolites and metabolic health affects all bodily systems. Not surprisingly, altered metabolic function is associated with a wide spectrum of dysfunctions in the central nervous system - including developmental disorders, acute nervous system injury, and neurodegenerative disorders. Accordingly, metabolism-based therapies offer significant promise as new category of treatment options designed to  Weiterlesen…

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Gattung/Form: Electronic books
Medientyp: Dokument, Internetquelle
Dokumenttyp: Internet-Ressource, Computer-Datei
Alle Autoren: Susan Masino; Detlev Boison
ISBN: 9781461439035 1461439035 1461439027 9781461439028
OCLC-Nummer: 809370630
Beschreibung: 1 online resource
Inhalt: Part 1. Introduction --
Adenosine and Metabolism--A Brief Historical Note / Bertil B. Fredholm. Part 2. Molecular biology, pharmacology, and cell biology of adenosine --
Adenosine Metabolism, Adenosine Kinase, and Evolution / Jaoek Park and Radhey S. Gupta --
Adenosine and Energy Metabolism--Relationship to Brain Bioenergetics / Xuesong Chen, Liang Hui and Jonathan D. Geiger --
Adenosine and Autocrine Metabolic Regulation of Neuronal Activity / Masahito Kawamura Jr. and David N. Ruskin --
Physiologic and Metabolic Regulation of Adenosine: Mechanisms / Chris G. Dulla and Susan A. Masino --
The Double-Edged Sword: Gaining Adenosine at the Expense of ATP. How to Balance the Books / Stephanie zur Nedden, Alexander S. Doney and Bruno G. Frenguelli --
Downstream Pathways of Adenosine / Ana M. Sebastião, Sofia Cristóvão-Ferreira and Joaquim A. Ribeiro --
Astrocytic ATP Release / Dustin J. Hines and Philip G. Haydon --
Role of Striatal A2A Receptor Subpopulations in Neurological Disorders / Sergi Ferré, César Quiroz, Marco Orrú, Xavier Guitart and Seema Gulyani, et al. Part 3. Adenosine function and dysfunction in brain health and disease --
Sleep and Adenosine: Human Studies / Tarja Porkka-Heiskanen --
Adenosine and Other Purinergic Products in Circadian Timing / Christine Muheim and Steven A. Brown --
Adenosine in the Immune System / György Haskó, Balázs Koscsó and Balázs Csóka --
The Bioenergetic Network of Adenosine in Hibernation, Sleep, and Thermoregulation / Kelly L. Drew and Tulasi R. Jinka --
Adenosine and Stroke / Felicita Pedata, Anna Maria Pugliese, Francesca Corti and Alessia Melani --
The Many Roles of Adenosine in Traumatic Brain Injury / Patrick M. Kochanek, Jonathan D. Verrier, Amy K. Wagner and Edwin K. Jackson --
Therapeutic Perspectives of Adenosine Receptor Compounds in Functional Restitution After Spinal Cord Injury / Kwaku D. Nantwi --
Adenosine and Pain / Jana Sawynok --
Symptomatic and Neuroprotective Effects of A2A Receptor Antagonists in Parkinson's Disease / Annalisa Pinna, Nicola Simola, Lucia Frau and Micaela Morelli --
Adenosine Receptors and Alzheimer's Disease / David Blum, Ursula Sandau, Cyril Laurent, Vânia Batalha and Antoine Leboucher, et al. --
Adenosine Receptors in Huntington's Disease / David Blum, Alberto Martire, Sylvie Burnouf, Bernard Sablonnière and Pierre Krystkowiak, et al. --
Adenosine and Multiple Sclerosis / María Victoria Sánchez-Gómez, Estibaliz González-Fernández, Rogelio O. Arellano and Carlos Matute --
Adenosinergic Perspectives on Schizophrenia: Opportunity for an Integrative Synthesis / Benjamin K. Yee, Philipp Singer and Detlev Boison --
The Role of Adenosine in the Ventral Striatal Circuits Regulating Behavioral Activation and Effort-Related Decision Making: Importance for Normal and Pathological Aspects of Motivation / John D. Salamone, Merce Correa, Patrick A. Randall, Eric J. Nunes and Marta Pardo, et al. --
Adenosine and Autism: Physiological Symptoms and Metabolic Opportunities / Julia Svedova, Inge-Marie Eigsti and Susan A. Masino --
Stress, Brain Adenosine Signaling, and Fatigue-Related Behavioral Processes / Traci N. Plumb, Sarah R. Sterlace, Kelly A. Cavanaugh and Thomas R. Minor. Part 4. Adenosine-based therapies --
Disruption of Adenosine Homeostasis in Epilepsy and Therapeutic Adenosine Augmentation / Detlev Boison --
Ketogenic Diet and Epilepsy: The Role of Adenosine / Jong M. Rho, Beth Zupec-Kania and Susan A. Masino --
Silk: A Biocompatible and Biodegradable Biopolymer for Therapeutic Adenosine Delivery / Eleanor M. Pritchard, Detlev Boison and David L. Kaplan --
Anatomical Distribution of Nucleoside System in the Human Brain and Implications for Therapy / Zsolt Kovács and Arpád Dobolyi.
Verfasserangabe: Susan Masino, Detlev Boison, editors.
Weitere Informationen:


Following on new understanding of its influence in dopaminergic disorders, sleep and epilepsy, this book collects recent research on regulating the influence of adenosine, outlines clinical  Weiterlesen…


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