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Adhesion molecules : function and inhibition

Author: Klaus Ley
Publisher: Basel ; Boston : Birkhauser, ©2007.
Series: PIR (Series)
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Inflammatory cell recruitment requires the concerted action of at least five major sets of adhesion molecules: integrins, immunoglobulin-like molecules, selectins, carbohydrate structures serving as selectin ligands, and certain ectoenzymes. This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Adhesion molecules.
Basel ; Boston : Birkhauser, ©2007
(DLC) 2007929896
(OCoLC)153582015
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Klaus Ley
ISBN: 9783764379759 3764379758 376437974X 9783764379742
OCLC Number: 261225084
Description: 1 online resource (xiv, 309 pages) : illustrations.
Contents: Capture and rolling --
P-selectin glycoprotein ligand-1 (PSGL-1) --
L-selectin-mediated leukocyte adhesion and migration --
P- and E-selectin --
Firm adhesion --
Endothelial ICAM-1 functions in adhesion and signaling during leukocyte recruitment --?4-integrins: structure, function and secrets --
VCAM-1 and its functions in development and inflammatory diseases --
Lymphocyte function-associated antigen-1 (LFA-1) and macrophage antigen-1 (Mac-1): Cooperative partners in leukocyte emigration and function --
Transendothelial migration --
PECAM: Regulating the start of diapedesis --
Role of?6?1 integrin in leukocyte adhesion and transmigration --
Vascular adhesion protein-1 (VAP-1) --
The role of endothelial cell-selective adhesion molecule (ESAM) in neutrophil emigration into inflamed tissues --
Structure and function of JAM proteins --
Promises and limitations of targeting adhesion molecules for therapy.
Series Title: PIR (Series)
Responsibility: Klaus Ley, editor.
More information:

Abstract:

This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the biology, structure,  Read more...

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From the reviews:"This book is a great and informative text to all those who wish to access and demystify the field of adhesion molecules. The monograph ... deals specifically with adhesion molecules Read more...

 
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