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Advances in cancer research. / Volume 70

Author: George F Vande Woude; George Klein
Publisher: San Diego : Academic Press, ©1996.
Series: Advances in cancer research, 70
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Volume 70 begins with two "Foundations in Cancer Research" articles, a staple of the Advances in Cancer Research series. The first article by Michael Stoker presents a review of some of the early advances made by cancer cell biology researchers. The second article by Emmanuel Farber describes the methods by which researchers delineate the phenotype of cells and ways to alter these phenotypes to prevent or delay  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Advances in cancer research. Volume 70.
San Diego : Academic Press, ©1996
(OCoLC)38975048
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: George F Vande Woude; George Klein
ISBN: 9780080562520 0080562523 012006670X 9780120066704
OCLC Number: 298067418
Description: 1 online resource (ix, 229 pages) : illustrations.
Contents: Foundations in Cancer Research:M. Stoker, Fundamentals of Cancer Cell Biology:Introduction.Antecedents.Autobiographical Note.Foundations of Tissue Culture.Foundations of Cell Culture.Clones.The Immortals: Stable Cell Lines.The Mortals: Cell Strains.Food for Cells in Culture.Growth Factors.Short-Range Cell Interactions.Junctional Communication.Cell and Substrate Adhesion.The Tumor Viruses.Cell Fusion.Conclusion.References.E. Farber, The Step-by-Step Development of Epithelial Cancer: From Phenotype to Genotype:Cancer Development as Basic to Cancer Research.Patterns of Development of Epithelial Cancers.A Working Hypothesis.The Phenotypes.The Genotypes.The Challenge.References.A. Chidambaram and M. Dean, Genetics of the Nevoid Basal Cell Carcinoma Syndrome:Introduction.Clinicopathological Features of NBCCS.Genetics of NBCCS.Strategies for Isolation of Candidate Genes.Discussion.References.K. Koli and J. Keski-Oja, Transforming Growth Factor-( System and Its Regulation by Members of the Steroid-Thyroid Hormone Superfamily:Introduction.Transforming Growth Factor-(. Dual Effects of TGF-(on Cell Proliferation.Regulation of Cell Differentiation by TGF-(. TGF-(in the Regulation of the Immune System.The Steroid-Thyroid Hormone Superfamily.Steroid Hormone Regulation of TGF-( Isoform Expression.Regulation of Plasminogen Activation by Steroids.Summary.References.J.-M. Lemaitre, R.S. Buckle, and M. Mechali, c-Mycin the Control of Cell Proliferation and Embryonic Development:Introduction.The c-myc Gene.Structural and Functional Features of the c-Myc Protein.c-Myc as a Transcription Factor.c-Myc and Cell Proliferation.c-Myc in Embryonic Development.c-Myc and Differentiation.c-Myc and Apoptosis.References.S.A. Rosenberg, Y. Kawakami, P.F. Robbins, and R.-F. Wang, Identification of the Genes Encoding Cancer Antigens: Implications for Cancer Immunotherapy.Introduction.Methodology.Human Melanoma Antigens Recognized by T Cells.Cancer Therapies Based on the Molecular Identification of Cancer Antigens.References.B.A.J. Ponder and D. Smith, The MEN II Syndromes and the Role of the ret Proto-oncogene:.Introduction.The MEN II Syndromes.The ret Proto-oncogene.Development of the Tissues Involved in MEN II, and Patterns of ret Expression.Speculations on How Different ret Mutations Result in the Associated Phenotypes and in Tumor Formation.Other Events in Tumor Progression.Animal Models of MEN II.Clinical Implications of the Identification of ret Mutations in MEN II.Future Prospects.References.Subject Index.
Series Title: Advances in cancer research, 70
Responsibility: edited by George F. Vande Woude, George Klein.

Abstract:

Presents a review of some of the early advances made by cancer cell biology researchers. This book describes the methods by which researchers delineate the phenotype of cells and ways to alter these  Read more...

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"This classic and essential series presents critical overviews on select aspects of both cancer research and the basic underlying sciences."--AMERICAN SCIENTIST"Excellent, highly informative, Read more...

 
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