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| Genre/Form: | Electronic books |
|---|---|
| Material Type: | Document, Internet resource |
| Document Type: | Internet Resource, Computer File |
| All Authors / Contributors: |
Frank J Dixon |
| ISBN: | 9786611020682 6611020683 0080522378 9780080522371 |
| OCLC Number: | 441781154 |
| Description: | 1 online resource (368 p.) |
| Contents: | Cover -- Title Page -- Copyright Page -- CONTENTS -- Contens of Recent Volumes -- Contributors -- Chapter 1. MIC Genes: From Genetics to Biology -- I. Introduction -- II. Genes and Genomics -- III. Transcripts and Transcription -- IV. Biochemistry and Biology -- V. Genetics and Immunogenetics -- VI. Conclusion -- References -- Chapter 2. CD40-Mediated Regulation of Immune Responses by TRAFDependent -- I. Introduction -- II. Discovery of CD40 and CD154 -- III. Functional Outcomes of CD154-CD40 Signaling -- IV. Regulation of CD40 and CD154 Expression -- V. Role of CD40-Induced Signaling Cascades in Functional Responses of B Cells -- VI. Conclusion -- References -- Chapter 3. Cell Death Control in Lymphocytes -- I. Introduction -- II. Apoptosis and the Role of Caspases -- III. Apoptosis Signaling by Death Receptors -- IV. Apoptosis Signaling through Apaf-1 and Caspase 9 -- V. Apoptosis and Its Regulation by Members of the Bcl-2 Family -- VI. Transcriptional and Posttranslational Control of Bcl-2 Family Members -- VII. Apoptosis and the Immune System -- VIII. T Cell Development-Apoptosis at the Pre-TCR Checkpoint -- IX. Positive and Negative Selection at the Pre-T Stage of Development -- X.T Cell Apoptosis in Peripheral Lymphoid Organs -- XI. The TNF-R Family and T Cell Proliferation -- XII. B Cell Development-Apoptosis at the Pre-BCR Checkpoint -- XIII. Selection of Immature B Cells in the Bone Marrow -- XIV. B Cell Apoptosis in Peripheral Lymphoid Organs -- XV. Conclusion -- References -- Chapter 4. Systemic Lupus Erythematosus, Complement Deficiency, and Apoptosis -- I. Introduction -- II. Description of the Associations between Complement and SLE in Humans -- III. Animal Models of Complement De.ciency -- IV. Complement and Inflammation in SLE -- V. Lupus Causes Autoantibody Production to C1q -- VI. Hypotheses for the Association between Complement Deficiency and SLE -- VII. What Lessons Can Be Learned from Other Murine Models of Autoimmunity? -- VIII. Conclusions -- References -- Chapter 5. Signal Transduction by the High-Affnity Immunoglobulin E Receptor FceRI: Coupling Form to Function -- I. Introduction -- II. Signal Initiation: The Central Importance of ITAM -- III. Phosphate Transfer and PTKs -- IV. Phosphate Transfer and PTPs -- V. Other Signaling Molecules -- VI. Integration of Lipid-Protein Interactions and Calcium Flux -- VII. From Lipid Signaling to Protein Serine-Threonine Protein Kinases -- VIII. Lipid Rafts -- IX. Conclusion -- References -- Index -- Last Page. |
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