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Advances in mitochondrial medicine

Author: Roberto Scatena; Patrizia Bottoni; B Giardina
Publisher: Dordrecht ; New York : Springer, ©2012.
Series: Advances in experimental medicine and biology, 942.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Mitochondria are far more than the powerhouse of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogenesis, cell death by apoptosis, several different signal transduction pathways mainly related to redox control of gene  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Advances in mitochondrial medicine.
Dordrecht ; New York : Springer, ©2012
(DLC) 2011945106
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Roberto Scatena; Patrizia Bottoni; B Giardina
ISBN: 9789400728691 9400728697
OCLC Number: 781097436
Description: 1 online resource (xii, 461 pages).
Contents: Part 1. Physiology and structure of Mitochondria / The Oxidative Phosphorylation System in Mammalian Mitochondria / Sergio Papa, Pietro Luca Martino, Giuseppe Capitanio, Antonio Gaballo and Domenico De Rasmo, et al. --
Physiology and Pathophysiology of Mitochondrial DNA / Hongzhi Li, Danhui Liu, Jianxin Lu and Yidong Bai --
Mitochondrial Ca2+ as a Key Regulator of Mitochondrial Activities / Tito Calì, Denis Ottolini and Marisa Brini --
Mitochondria and Nitric Oxide: Chemistry and Pathophysiology / Paolo Sarti, Marzia Arese, Elena Forte, Alessandro Giuffrè and Daniela Mastronicola --
Mitochondria and Reactive Oxygen Species. Which Role in Physiology and Pathology? / Giorgio Lenaz --
Uncoupling Proteins: Molecular, Functional, Regulatory, Physiological and Pathological Aspects / Francis E. Sluse --
The Mitochondrial Pathways of Apoptosis / Jérome Estaquier, François Vallette, Jean-Luc Vayssiere and Bernard Mignotte --
Part 2. Mitochondria and disease / Inherited Mitochondrial Disorders / Josef Finsterer --
Role of Mitochondrial Function in Insulin Resistance / Myrte Brands, Arthur J. Verhoeven and Mireille J. Serlie --
Mitochondria and Diabetes. An Intriguing Pathogenetic Role / Philip Newsholme, Celine Gaudel and Maurico Krause --
Mitochondria and Heart Disease / Elinor J. Griffiths --
Mitochondria in Neurodegeneration / E Lezi and Russell H. Swerdlow --
Mitochondria and Cancer: A Growing Role in Apoptosis, Cancer Cell Metabolism and Dedifferentiation / Roberto Scatena --
Part 3. Mitochondria and Aging / Mitochondria and Aging / Hsin-Chen Lee and Yau-Huei Wei --
Mitochondria and Drugs / Roberto Scatena --
Iatrogenic Mitochondriopathies: A Recent Lesson from Nucleoside/Nucleotide Reverse Transcriptase Inhibitors / George P.H. Leung --
Dysfunction of Mitochondrial Respiratory Chain Complex I in Neurological Disorders: Genetics and Pathogenetic Mechanisms / Vittoria Petruzzella, Anna Maria Sardanelli, Salvatore Scacco, Damiano Panelli and Francesco Papa, et al. --
Anthracyclines and Mitochondria / Alvaro Mordente, Elisabetta Meucci, Andrea Silvestrini, Giuseppe Ettore Martorana and Bruno Giardina --
Mitochondrial Proteomic Approaches for New Potential Diagnostic and Prognostic Biomarkers in Cancer / Patrizia Bottoni, Bruno Giardina, Alessandro Pontoglio, Salvatore Scarà and Roberto Scatena --
Mitochondria in Anthropology and Forensic Medicine / Tomasz Grzybowski and Urszula Rogalla.
Series Title: Advances in experimental medicine and biology, 942.
Responsibility: Roberto Scatena, Patrizia Bottoni, Bruno Giardina, editors.
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Abstract:

This book discusses the role of mitochondrial dysfunction and the complex pathophysiological mechanisms associated with a growing number of illnesses. It examines mitochondria as a valuable target  Read more...

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