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Androgen-responsive genes in prostate cancer : regulation, function and clinical applications

Auteur : Zhou Wang
Éditeur : New York ; London : Springer, 2013.
Édition/format :   Livre électronique : Document : EnglishVoir toutes les éditions et tous les formats
Base de données :WorldCat
Résumé :
Recent studies demonstrated a key role of the androgen receptor in the development of castration-recurrent or -resistant prostate cancer (CRPC), which is deadly and in urgent need of more effective therapies. Understanding the functions of androgen-responsive genes and their regulation and deregulation in prostate cancer progression may lead to new approaches to prevent and treat prostate cancer patients. This book  Lire la suite...
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Détails

Genre/forme : Electronic books
Format – détails additionnels : Print version:
Androgen-responsive genes in prostate cancer.
New York ; London : Springer, 2013
(OCoLC)816164799
Type d’ouvrage : Document, Ressource Internet
Format : Internet Resource, Computer File
Tous les auteurs / collaborateurs : Zhou Wang
ISBN : 9781461461821 1461461820
Numéro OCLC : 828148221
Description : 1 online resource
Contenu : Roles of Androgen Receptor Coregulators and Cell Signaling in the Regulation of Androgen-Responsive Genes / Irina U. Agoulnik, Nancy L. Weigel --
Selective and Classical Androgen Response Elements in Androgen-Regulated Gene Expression / Frank Claessens, Liesbeth Clinckemalie --
Negative Androgen-Response Elements in Androgen Target Genes / Wei Qi, Zhengxin Wang --
Chromatin Looping and Long Distance Regulation by Androgen Receptor / Benjamin Sunkel, Qianben Wang --
The Functionality of Prostate Cancer Predisposition Risk Regions Is Revealed by AR Enhancers / Houtan Noushmehr, Simon G. Coetzee --
Mechanisms of ARE-Independent Gene Activation by the Androgen Receptor in Prostate Cancer Cells: Potential Targets for Better Intervention Strategies / Manohar Ratnam, Mugdha Patki, Mesfin Gonit --
Androgen Action, Wnt Signaling, and Prostate Tumorigenesis / Zijie Sun, Suk Hyung Lee --
Toward Revealing the Complexity of Androgen-Responsive Protein and Noncoding Transcripts in Prostate Cancer / Melanie L. Lehman, Colleen C. Nelson --
Androgen-Responsive Gene Expression in Prostate Cancer Progression / Amy H. Tien, Marianne D. Sadar --
Androgen Receptor-Regulated Genes in Prostate Cancer Initiation Versus Metastasis / Soo Ok Lee, Chiung-Kuei Huang, Luo Jie. Androgen-Independent Induction of Androgen-Responsive Genes by Interleukin-6 Regulation / Zoran Culig --
The Effect of AR Overexpression on Androgen Signaling in Prostate Cancer / Alfonso Urbanucci, Kati K. Waltering --
The Expression Signature of Androgen Receptor Splice Variants and Their Distinctive Transcriptional Activities in Castration-Resistant Prostate Cancer / Stephen R. Plymate, Jun Luo --
Androgen Regulation of the Cell Cycle in Prostate Cancer / Haojie Huang --
Androgen Receptor Signaling Interactions Control Epithelial-Mesenchymal Transition (EMT) in Prostate Cancer Progression / Sarah K. Martin, Michael V. Fiandalo --
Androgen Receptor Regulation of Serum Response Factor Signaling in Prostate Cancer / Alissa R. Verone, Hannelore V. Heemers --
Regulation of Angiogenesis by Androgen-Responsive Gene EAF2 / Laura E. Pascal, Zhou Wang --
The Role of miR-21, an Androgen-Regulated MicroRNA, in Prostate Cancer / Judit Ribas, Shawn E. Lupold --
Androgen-Dependent Oncogenic Activation of ETS Transcription Factors by Recurrent Gene Fusions in Prostate Cancer: Biological and Clinical Implications / Albert Dobi, Taduru Sreenath --
Clusterin as a Target for Treatment of Castration-Resistant Prostate Cancer / Amina Zoubeidi.
Responsabilité : edited by Zhou Wang.
Plus d’informations :

Résumé :

This book examines current understanding of mechanisms underlying the regulation of androgen-responsive gene expression, and functions of androgen-responsive genes in carcinogenesis, including cell  Lire la suite...

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