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Angiogenesis modulations in health and disease : practical applications of pro- and antiangiogenesis targets

Autor: Shaker A Mousa; Paul J Davis, (Professor of pharmacy)
Editora: Dordrecht : Springer, [2013]
Edição/Formato   Print book : InglêsVer todas as edições e formatos
Base de Dados:WorldCat
Resumo:

This book offers in-depth explanations of pro-angiogenesis and anti-angiogenesis targets and their evaluation methods. Coverage includes preclinical and clinical methods and models, investigational  Ler mais...

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Tipo de Documento: Livro
Todos os Autores / Contribuintes: Shaker A Mousa; Paul J Davis, (Professor of pharmacy)
ISBN: 9789400764668 9400764669 9400764677 9789400764675
Número OCLC: 862322069
Descrição: x, 206 pages : illustrations
Conteúdos: Preface. 1. Angiogenesis assays: an appraisal of current techniques. 2. Survey of pro-angiogenesis strategies. 3. Angiogenesis modulation by arachidonic acid - derived lipids: positive and negative regulators of angiogenesis. 4. Pro-angiogenic activity of thyroid hormone analogues: Mechanisms, physiology and clinical prospects. 5. Actions of steroids and peptide hormones on angiogenesis. 6. Role of non-neuronal nicotinic acetylcholine receptors in angiogenesis modulation. 7. Catecholamine neurotransmitters: an angiogenic switch in the tumor microenvironment. 8. Impact of nanotechnology on therapeutic angiogenesis. 9. Survey of anti-angiogenesis strategies. 10. Tetraiodothyroacetic acid (tetrac), nanotetrac and anti-Angiogenesis. 11. Integrin antagonists and angiogenesis. 12. Anti-angiogenesis therapy as an adjunct to chemotherapy in oncology. 13. Anti-vegf strategies in ocular angiogenesis- mediated disorders, with special emphasis on age-related macular degeneration. 14. Application of nanotechnology to targeting tumor angiogenesis for therapeutic benefit. 15. Biomarkers of response and resistance to anti-angiogenic treatment.16. Speculations on new directions in which angiogenesis may proceed. Index.
Responsabilidade: Shaker A. Mousa, Paul J. Davis, editors.

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