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Animal Cell Culture

Author: Mohamed Al-Rubeai
Publisher: Cham : Springer International Publishing : Imprint : Springer, 2015.
Series: Cell engineering, 9.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Animal cells are the preferred ℓ́ℓcell factoriesℓ́ℓ for the production of complex molecules and antibodies for use as prophylactics, therapeutics or diagnostics. Animal cells are required for the correct post-translational processing (including glycosylation) of biopharmaceutical protein products. They are used for the production of viral vectors for gene therapy. Major targets for this therapy include cancer, HIV,  Read more...
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Additional Physical Format: Printed edition:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Mohamed Al-Rubeai
ISBN: 9783319103204 3319103202 9783319103198 3319103199
OCLC Number: 900364125
Description: 1 online resource (xii, 763 pages) : illustrations.
Contents: 1. Cell line development / Hansjoerg Hauser --
2. Transient recombinant protein expression in mammalian cells / Volker Jäger, Konrad Büssow, and Thomas Schirrmann --
3. Production of antibodies in hybridoma and non-hybridoma cell lines / Susan McDonnell --
4. Bioreactors for mammalian cells / R. Pörtner --
5. Mass transfer and mixing across the scales in animal cell culture / Alvin W. Nienow --
6. Hydrodynamic damage to animal cells / Jeffrey J. Chalmers and Ningning Ma --
7. Monitoring of cell culture / Sebastian Schwamb, Robert Puskeiler and Philipp Wiedemann --
8. Serum and protein free media / Michael Butler --
9. Glycosylation in cell culture / Maureen Spearman and Michael Butler --
10. Modelling of mammalian cell cultures / Nishikant P. Shirsat [and others] --
11. Mammalian cell line selection strategies for high-producers / Darrin Kuystermans and Mohamed Al-Rubeai --
12. Building a cell culture process with stable foundations: searching for certainty in an uncertain world / Peter M. O'Callaghan and Andrew J. Racher --
13. Perfusion processes / Véronique Chotteau --
14. Single-use bioreactors for animal and human cells / Stephan C. Kaiser [and others] --
15. An overview of cell culture engineering for the insect cell-baculovirus expression vector system (BEVS) / Laura A. Palomares, Mauricio Realpe and Octavio T. Ramírez --
16. Metabolic flux analysis: a powerful tool in animal cell culture / João V. Sá [and others] --
17. Cell immobilization for the production of viral vaccines / Ana Carina Silva [and others] --
18. Cell engineering for therapeutic protein production / Eric Baek [and others] --
19. Proteomics in cell culture: from genomics to combines 'omics for cell line engineering and bioprocess development / Kelley Heffner [and others] --
20. Metabolomics in animal cell culture / Miroslava Čuperlović-Culf --
21. Process analytical technology and quality-by-design for animal cell culture / Stephen Craven and Jessica Whelan --
22. Biosafety recommendations on the handling of animal cell cultures / Philippe Herman and Katia Pauwels --
23. Biopharmaceutical products from animal cell culture / Darrin Kuystermans and Mohamed Al-Rubeai.
Series Title: Cell engineering, 9.
Responsibility: edited by Mohamed Al-Rubeai.
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