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Animal models for human cancer : discovery and development of novel therapeutics

Author: Marianne I Martic-Kehl; P A Schubiger
Publisher: Weinheim, Germany : Wiley-VCH, 2016.
Series: Methods and principles in medicinal chemistry, vol. 69.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results. Following a short historical introduction and a discussion of the ethics surrounding animal experiments, the book describes correct study design as well as the handling and  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Martic-Kehl, Marianne I.
Animal Models for Human Cancer : Discovery and Development of Novel Therapeutics.
Hoboken : Wiley, ©2016
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Marianne I Martic-Kehl; P A Schubiger
ISBN: 9783527695881 3527695885 9783527695898 3527695893
OCLC Number: 950459591
Description: 1 online resource.
Contents: Chapter 1. Introduction --
Chapter 2. Ethical aspects of the use of animals in translational research --
Chapter 3. Study design --
Chapter 4. Improving external validity of experimental animal data --
Chapter 5. How to end selective reporting in animal research --
Chapter 6. A comprehensive overview of mouse models in oncology --
Chapter 7. Mouse models of advanced spontaneous metastasis for experiemental therapeutics --
Chapter 8. Spontaneous animal tumor models --
Chapter 9. Dog models of naturally occurring cancer --
Chapter 10. Improving preclincal cancer models: lessons from human and canine clinical trials of metronomic chemotherapy .
Series Title: Methods and principles in medicinal chemistry, vol. 69.
Responsibility: edited by Marianne I. Martic-Kehl and P. August Schubiger.

Abstract:

Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized  Read more...

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