跳到内容
Antibiotic resistance 预览资料
关闭预览资料
正在查...

Antibiotic resistance

著者: Anthony R M Coates
出版商: Heidelberg : Springer, ©2012.
丛书: Handbook of experimental pharmacology, 211.
版本/格式:   电子图书 : 文献 : 英语查看所有的版本和格式
提要:
This book describes antibiotic resistance amongst pathogenic bacteria. It starts with an overview of the erosion of the efficacy of antibiotics by resistance and the decrease in the rate of replacement of redundant compounds. The origins of antibiotic resistance are then described. It is proposed that there is a large bacterial resistome which is a collection of all resistance genes and their precursors in both  再读一些...
评估:

(尚未评估) 0 附有评论 - 争取成为第一个。

主题
更多类似这样的

 

在线查找

与资料的链接

在图书馆查找

&AllPage.SpinnerRetrieving; 正在查找有这资料的图书馆...

详细书目

类型/形式: Electronic books
附加的形体格式: Print version:
Antibiotic resistance.
Heidelberg : Springer, ©2012
(DLC) 2012950770
(OCoLC)820967967
材料类型: 文献, 互联网资源
文档类型 互联网资源, 计算机文档
所有的著者/提供者: Anthony R M Coates
ISBN: 9783642289514 3642289517 9783642289507 3642289509
OCLC号码: 817540373
描述: 1 online resource (viii, 190 pages) : illustrations.
内容: Introduction to antibiotic resistance/ Richard Bax, David Griffin --
The origins of antibiotic resistance/ Gerard D. Wright --
Surveillance programmes and antibiotic resistance: worldwide and regional monitoring of antibiotic resistance trends/ Stephen Hawser --
Current and future challenges in the development of antimicrobial agents/ Robert P. Rennie --
The role of the outer membrane of gram-negative bacteria in antibiotic resistance: Ajax' shield or Achilles' heel?/ Malcolm G.P. Page --
Prevention of drug resistance by combined drug treatment of tuberculosis/ Denis A. Mitchison --
Nonmultiplying bacteria are profoundly tolerant to antibiotics/ Yanmin Hu, Anthony Coates --
Persister cells: molecular mechanisms related to antibiotic tolerance/ Kim Lewis --
Antimicrobial textiles/ J. Vaun McArthur, R.C. Tuckfield, C. Baker-Austin --
Efflux: how bacteria use pumps to control their microenvironment/ E. David G. McIntosh --
Antibiotics in phase II and III clinical trials/ Anthony R.M. Coates, Gerry Halls.
丛书名: Handbook of experimental pharmacology, 211.
责任: Anthony R.M. Coates, editor.

摘要:

This book describes antibiotic resistance amongst pathogenic bacteria. It starts with an overview of the erosion of the efficacy of antibiotics by resistance and the decrease in the rate of replacement of redundant compounds. The origins of antibiotic resistance are then described. It is proposed that there is a large bacterial resistome which is a collection of all resistance genes and their precursors in both pathogenic and non-pathogenic bacteria. Ongoing resistance surveillance programs are also discussed, together with the perspective of a clinical microbiologist. The book then turns to specific themes such as the most serious area of resistance in pathogens, namely in Gram-negative organisms. The role of combinations of antibiotics in combating resistance emergence is discussed, particularly in the tuberculosis field, and then the importance of non-multiplying and persistent bacteria which are phenotypically resistant to antibiotics and prolong the duration of therapy of antibiotics which leads to poor compliance and resistance emergence. The role of anti-microbial compounds in textiles is covered, with its potential to exacerbate the spread of resistance. Then, efflux pumps are discussed. The final chapter describes the compounds which are in late stage clinical development, illustrating the paucity of the antibiotic pipeline, especially for Gram-negative bacteria.

评论

用户提供的评论
正在获取GoodReads评论...
正在检索DOGObooks的评论

标签

争取是第一个!

相似资料

主题:(8)

这资料的用户列表 (4)

确认申请

你可能已经申请过这份资料。如果还是想申请,请选确认。

链接数据


Primary Entity

<http://www.worldcat.org/oclc/817540373> # Antibiotic resistance
    a schema:CreativeWork, schema:Book, schema:MediaObject ;
    library:oclcnum "817540373" ;
    library:placeOfPublication <http://experiment.worldcat.org/entity/work/data/1180970745#Place/heidelberg> ; # Heidelberg
    library:placeOfPublication <http://id.loc.gov/vocabulary/countries/gw> ;
    schema:about <http://id.worldcat.org/fast/898704> ; # Drug resistance in microorganisms
    schema:about <http://id.loc.gov/authorities/subjects/sh85005638> ; # Antibiotics
    schema:about <http://id.loc.gov/authorities/subjects/sh85039709> ; # Drug resistance in microorganisms
    schema:about <http://experiment.worldcat.org/entity/work/data/1180970745#Topic/drug_resistance_in_microorganisms_immunology> ; # Drug resistance in microorganisms--Immunology
    schema:about <http://experiment.worldcat.org/entity/work/data/1180970745#Topic/anti_bacterial_agents_therapeutic_use> ; # Anti-Bacterial Agents--therapeutic use
    schema:about <http://id.loc.gov/authorities/subjects/sh85090243> ; # Natural immunity
    schema:about <http://experiment.worldcat.org/entity/work/data/1180970745#Topic/drug_discovery> ; # Drug Discovery
    schema:about <http://id.worldcat.org/fast/1034361> ; # Natural immunity
    schema:about <http://id.worldcat.org/fast/810420> ; # Antibiotics
    schema:about <http://experiment.worldcat.org/entity/work/data/1180970745#Topic/drug_resistance_microbial> ; # Drug Resistance, Microbial
    schema:about <http://dewey.info/class/616.9041/e23/> ;
    schema:about <http://experiment.worldcat.org/entity/work/data/1180970745#Topic/medical_microbiology> ; # MEDICAL--Microbiology
    schema:bookFormat schema:EBook ;
    schema:contributor <http://viaf.org/viaf/70759885> ; # Anthony R. M. Coates
    schema:copyrightYear "2012" ;
    schema:datePublished "2012" ;
    schema:description "This book describes antibiotic resistance amongst pathogenic bacteria. It starts with an overview of the erosion of the efficacy of antibiotics by resistance and the decrease in the rate of replacement of redundant compounds. The origins of antibiotic resistance are then described. It is proposed that there is a large bacterial resistome which is a collection of all resistance genes and their precursors in both pathogenic and non-pathogenic bacteria. Ongoing resistance surveillance programs are also discussed, together with the perspective of a clinical microbiologist. The book then turns to specific themes such as the most serious area of resistance in pathogens, namely in Gram-negative organisms. The role of combinations of antibiotics in combating resistance emergence is discussed, particularly in the tuberculosis field, and then the importance of non-multiplying and persistent bacteria which are phenotypically resistant to antibiotics and prolong the duration of therapy of antibiotics which leads to poor compliance and resistance emergence. The role of anti-microbial compounds in textiles is covered, with its potential to exacerbate the spread of resistance. Then, efflux pumps are discussed. The final chapter describes the compounds which are in late stage clinical development, illustrating the paucity of the antibiotic pipeline, especially for Gram-negative bacteria."@en ;
    schema:exampleOfWork <http://worldcat.org/entity/work/id/1180970745> ;
    schema:genre "Electronic books"@en ;
    schema:inLanguage "en" ;
    schema:isPartOf <http://experiment.worldcat.org/entity/work/data/1180970745#Series/handbook_of_experimental_pharmacology> ; # Handbook of experimental pharmacology ;
    schema:isSimilarTo <http://www.worldcat.org/oclc/820967967> ;
    schema:name "Antibiotic resistance"@en ;
    schema:productID "817540373" ;
    schema:publication <http://www.worldcat.org/title/-/oclc/817540373#PublicationEvent/heidelberg_springer_2012> ;
    schema:publisher <http://experiment.worldcat.org/entity/work/data/1180970745#Agent/springer> ; # Springer
    schema:url <http://site.ebrary.com/id/10617950> ;
    schema:url <http://www.myilibrary.com?id=405320> ;
    schema:url <http://public.eblib.com/choice/publicfullrecord.aspx?p=972201> ;
    schema:url <http://dx.doi.org/10.1007/978-3-642-28951-4> ;
    schema:url <https://link.springer.com/openurl?genre=book&isbn=978-3-642-28950-7> ;
    schema:url <http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=511458> ;
    schema:url <http://link.springer.com/openurl?genre=book&isbn=978-3-642-28950-7> ;
    schema:url <http://www.myilibrary.com?id=405320&ref=toc> ;
    schema:url <https://login.proxy.lib.strath.ac.uk/login?url=http://dx.doi.org/10.1007/978-3-642-28951-4> ;
    schema:url <https://grinnell.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-642-28951-4> ;
    schema:workExample <http://worldcat.org/isbn/9783642289514> ;
    schema:workExample <http://worldcat.org/isbn/9783642289507> ;
    wdrs:describedby <http://www.worldcat.org/title/-/oclc/817540373> ;
    .


Related Entities

<http://experiment.worldcat.org/entity/work/data/1180970745#Series/handbook_of_experimental_pharmacology> # Handbook of experimental pharmacology ;
    a bgn:PublicationSeries ;
    schema:hasPart <http://www.worldcat.org/oclc/817540373> ; # Antibiotic resistance
    schema:name "Handbook of experimental pharmacology ;" ;
    .

<http://experiment.worldcat.org/entity/work/data/1180970745#Topic/anti_bacterial_agents_therapeutic_use> # Anti-Bacterial Agents--therapeutic use
    a schema:Intangible ;
    schema:name "Anti-Bacterial Agents--therapeutic use"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/1180970745#Topic/drug_resistance_in_microorganisms_immunology> # Drug resistance in microorganisms--Immunology
    a schema:Intangible ;
    schema:hasPart <http://id.loc.gov/authorities/subjects/sh85039709> ; # Drug resistance in microorganisms
    schema:name "Drug resistance in microorganisms--Immunology"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/1180970745#Topic/drug_resistance_microbial> # Drug Resistance, Microbial
    a schema:Intangible ;
    schema:name "Drug Resistance, Microbial"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/1180970745#Topic/medical_microbiology> # MEDICAL--Microbiology
    a schema:Intangible ;
    schema:name "MEDICAL--Microbiology"@en ;
    .

<http://id.loc.gov/authorities/subjects/sh85005638> # Antibiotics
    a schema:Intangible ;
    schema:name "Antibiotics"@en ;
    .

<http://id.loc.gov/authorities/subjects/sh85039709> # Drug resistance in microorganisms
    a schema:Intangible ;
    schema:name "Drug resistance in microorganisms"@en ;
    .

<http://id.loc.gov/authorities/subjects/sh85090243> # Natural immunity
    a schema:Intangible ;
    schema:name "Natural immunity"@en ;
    .

<http://id.worldcat.org/fast/1034361> # Natural immunity
    a schema:Intangible ;
    schema:name "Natural immunity"@en ;
    .

<http://id.worldcat.org/fast/810420> # Antibiotics
    a schema:Intangible ;
    schema:name "Antibiotics"@en ;
    .

<http://id.worldcat.org/fast/898704> # Drug resistance in microorganisms
    a schema:Intangible ;
    schema:name "Drug resistance in microorganisms"@en ;
    .

<http://link.springer.com/openurl?genre=book&isbn=978-3-642-28950-7>
    rdfs:comment "Springer eBooks (Biomedical and Life Sciences 2012)" ;
    .

<http://viaf.org/viaf/70759885> # Anthony R. M. Coates
    a schema:Person ;
    schema:familyName "Coates" ;
    schema:givenName "Anthony R. M." ;
    schema:name "Anthony R. M. Coates" ;
    .

<http://worldcat.org/isbn/9783642289507>
    a schema:ProductModel ;
    schema:isbn "3642289509" ;
    schema:isbn "9783642289507" ;
    .

<http://worldcat.org/isbn/9783642289514>
    a schema:ProductModel ;
    schema:isbn "3642289517" ;
    schema:isbn "9783642289514" ;
    .

<http://www.worldcat.org/oclc/820967967>
    a schema:CreativeWork ;
    rdfs:label "Antibiotic resistance." ;
    schema:description "Print version:" ;
    schema:isSimilarTo <http://www.worldcat.org/oclc/817540373> ; # Antibiotic resistance
    .


Content-negotiable representations

关闭窗口

请登入WorldCat 

没有张号吗?很容易就可以 建立免费的账号.