skip to content
Antibiotics : challenges, mechanisms, opportunities Preview this item
ClosePreview this item
Checking...

Antibiotics : challenges, mechanisms, opportunities

Author: Christopher Walsh; Timothy A Wencewicz
Publisher: Washington, DC : ASM Press, [2016] ©2016
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Antibiotics focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets.
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

 

Find a copy online

Links to this item

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Genre/Form: Electronic books
Additional Physical Format: Print version:
Walsh, Christopher.
Antibiotics.
Washington, DC : ASM Press, [2016]
(DLC) 2015045498
(OCoLC)931476697
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Christopher Walsh; Timothy A Wencewicz
ISBN: 9781555819316 1555819311
OCLC Number: 931861088
Description: 1 online resource (x, 477 pages)
Contents: --
Preface --
Chapter 1 : Antibiotics: Initial Concepts and Considerations --
Chapter 2 : Major Classes of Antibiotics and Their Modes of Action --
Chapter 3 : Assembly of the Peptidoglycan Layer of Bacterial Cell Walls --
Chapter 4 : Antibiotics That Block Peptidoglycan Assembly and Integrity --
Chapter 5 : Antibiotics That Disrupt Membrane Integrity --
Chapter 6 : Antibiotics That Block Protein Synthesis --
Chapter 7 : Antibiotics That Target DNA and RNA Information Transfer --
Chapter 8 : Antibiotics That Block Biosynthesis of the DNA Building Block Deoxythymidylate --
Chapter 9 : Bacterial Antibiotic Resistance: Overview --
Chapter 10 : Antibiotic Resistance: Modification or Destruction of the Antibiotic --
Chapter 11 : Antibiotic Resistance via Membrane Efflux Pumps --
Chapter 12 : Resistance via Target Modification --
Chapter 13 : Tuberculosis: A Formidable Challenge for Antibiotic Therapy --
Chapter 14 : Antibiotic Biosynthesis: Principles --
Chapter 15 : Biosynthesis of Peptide Antibiotics --
Chapter 16 : Biosynthesis of Polyketide Antibiotics --
Chapter 17 : Biosynthesis of Oligosaccharide, Isoprenoid, and C-P Antibiotic Classes --
Chapter 18 : Underexploited Pathways and Targets for Antibiotics --
Chapter 19 : Prospects for New Molecules and New Targets --
References --
Index.
Responsibility: by Christopher T. Walsh and Timothy A. Wencewicz.

Abstract:

Focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Applicable for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology  Read more...

Reviews

Editorial reviews

Publisher Synopsis

This book provides all the information needed to understand antibiotic genetics, biochemistry, mechanism of action and resistance. Most importantly, Walsh & Wencewicz are optimistic of the prospects Read more...

 
User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


Primary Entity

<http://www.worldcat.org/oclc/931861088> # Antibiotics : challenges, mechanisms, opportunities
    a schema:MediaObject, schema:Book, schema:CreativeWork ;
   library:oclcnum "931861088" ;
   library:placeOfPublication <http://id.loc.gov/vocabulary/countries/dcu> ;
   schema:about <http://experiment.worldcat.org/entity/work/data/2826348694#Topic/anti_bacterial_agents> ; # Anti-Bacterial Agents
   schema:about <http://experiment.worldcat.org/entity/work/data/2826348694#Topic/drug_resistance_microbial> ; # Drug Resistance, Microbial
   schema:about <http://experiment.worldcat.org/entity/work/data/2826348694#Topic/antibiotics> ; # Antibiotics
   schema:about <http://experiment.worldcat.org/entity/work/data/2826348694#Topic/medical_pharmacology> ; # MEDICAL / Pharmacology
   schema:about <http://experiment.worldcat.org/entity/work/data/2826348694#Topic/drug_resistance_in_microorganisms> ; # Drug resistance in microorganisms
   schema:about <http://dewey.info/class/615.329/e23/> ;
   schema:author <http://experiment.worldcat.org/entity/work/data/2826348694#Person/wencewicz_timothy_a> ; # Timothy A. Wencewicz
   schema:author <http://experiment.worldcat.org/entity/work/data/2826348694#Person/walsh_christopher> ; # Christopher Walsh
   schema:bookFormat schema:EBook ;
   schema:copyrightYear "2016" ;
   schema:datePublished "2016" ;
   schema:description "Antibiotics focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets."@en ;
   schema:exampleOfWork <http://worldcat.org/entity/work/id/2826348694> ;
   schema:genre "Electronic books"@en ;
   schema:inLanguage "en" ;
   schema:isSimilarTo <http://www.worldcat.org/oclc/931476697> ;
   schema:name "Antibiotics : challenges, mechanisms, opportunities"@en ;
   schema:productID "931861088" ;
   schema:url <http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=1180027> ;
   schema:url <http://www.asmscience.org/content/book/10.1128/9781555819316> ;
   schema:url <http://www.r2library.com/Resource/Title/1555819303> ;
   schema:url <http://public.eblib.com/choice/PublicFullRecord.aspx?p=4427095> ;
   schema:url <http://dx.doi.org/10.1128/9781555819316> ;
   schema:workExample <http://worldcat.org/isbn/9781555819316> ;
   wdrs:describedby <http://www.worldcat.org/title/-/oclc/931861088> ;
    .


Related Entities

<http://experiment.worldcat.org/entity/work/data/2826348694#Person/walsh_christopher> # Christopher Walsh
    a schema:Person ;
   schema:familyName "Walsh" ;
   schema:givenName "Christopher" ;
   schema:name "Christopher Walsh" ;
    .

<http://experiment.worldcat.org/entity/work/data/2826348694#Person/wencewicz_timothy_a> # Timothy A. Wencewicz
    a schema:Person ;
   schema:familyName "Wencewicz" ;
   schema:givenName "Timothy A." ;
   schema:name "Timothy A. Wencewicz" ;
    .

<http://experiment.worldcat.org/entity/work/data/2826348694#Topic/anti_bacterial_agents> # Anti-Bacterial Agents
    a schema:Intangible ;
   schema:name "Anti-Bacterial Agents"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/2826348694#Topic/drug_resistance_in_microorganisms> # Drug resistance in microorganisms
    a schema:Intangible ;
   schema:name "Drug resistance in microorganisms"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/2826348694#Topic/drug_resistance_microbial> # Drug Resistance, Microbial
    a schema:Intangible ;
   schema:name "Drug Resistance, Microbial"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/2826348694#Topic/medical_pharmacology> # MEDICAL / Pharmacology
    a schema:Intangible ;
   schema:name "MEDICAL / Pharmacology"@en ;
    .

<http://worldcat.org/isbn/9781555819316>
    a schema:ProductModel ;
   schema:isbn "1555819311" ;
   schema:isbn "9781555819316" ;
    .

<http://www.worldcat.org/oclc/931476697>
    a schema:CreativeWork ;
   rdfs:label "Antibiotics." ;
   schema:description "Print version:" ;
   schema:isSimilarTo <http://www.worldcat.org/oclc/931861088> ; # Antibiotics : challenges, mechanisms, opportunities
    .


Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.