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The antibodies. Volume 6

Author: M Zanetti; J Donald Capra
Publisher: Amsterdam, Netherlands : Harwood Academic Publishers, ©2000.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
The Antibodies presents models, theories, and techniques of molecular biology for understanding the mechanisms of antibody action, including the genetics, and receptor and channel action. This book includes applications of engineered antibodies in diagnosis, immunotherapy, and protein purification. It provides new insights into the structural basis for antigen binding, effector functions, and regulation of the  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Antibodies. Volume 6.
Amsterdam, Netherlands : Harwood Academic Publishers, ©2000
(OCoLC)50237014
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: M Zanetti; J Donald Capra
ISBN: 0203305078 9780203305072
OCLC Number: 56729329
Description: 1 online resource (xiv, 281 pages) : illustrations
Contents: Regulation and expression of immunoglobulin / Heavy Chains --
Antibody-based mechanisms of tumor immunity / Allison M. Watts, Ronald C. Kennedy, and Robert K. Bright --
The human antibody repertoire: old notions, current realities, and Vh gene-dependent biases / Annuska M. Glas, Erwin H.N. van Montfort, and Eric C.B. Milner --
Understanding human immunoglobulin repertoires in vivo and evolving specificities in vitro / M. Ohlin [and others] --
Molecular dissection of the human antibody repertoire in systemic autoimmunity / Moncef Zouali --
Immunoglobulin V gene sequence analyses distinguish two subsets of chronic lymphocytic leukemia B cells / Franco Fais [and others] --
Regulation of B-Cell activation by the co-receptors: the CD19 connection / Sidne A. Omori, Dennis C. Otero, and Robert C. Rickert --
B-cell superantigens: an overview of structural, evolutionary, and immunobiologic considerations / Gregg J. Silverman.
Responsibility: edited by Maurizio Zanetti and J. Donald Capra.

Abstract:

The Antibodies presents models, theories, and techniques of molecular biology for understanding the mechanisms of antibody action, including the genetics, and receptor and channel action. This book includes applications of engineered antibodies in diagnosis, immunotherapy, and protein purification. It provides new insights into the structural basis for antigen binding, effector functions, and regulation of the immune response. The authors focus on the most essential and promising advances in antibody engineering, and on building immunoglobulins for therepeutic applications.

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