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Antitumor Drug Radiation Interactions

Author: Bridget T Hill; Angela S Bellamy
Publisher: Boca Raton, FL : CRC Press, 2018.
Series: CRC revivals.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
"This volume reviews the experimental data on drug-radiation interactions. Special emphasis is placed on clinically-useful antitumor drugs. Particular reference is made to appropriate timing, concentration and sequencing of drug-radiation combinations. It includes discussions on the relative merits of experimental data derived from animal versus human tumors. This book also presents a section on the potential for  Read more...
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Bridget T Hill; Angela S Bellamy
ISBN: 9781351069717 1351069713
OCLC Number: 1019680833
Description: 1 online resource.
Contents: Cover; Title Page; Copyright Page; Table of Contents; Chapter 1 Fundamental Concepts Associated with Combining Cytotoxic Drugs and X-Irradiation; Chapter 2 Radiation Damage Interactions with Actinomycin D and Adriamycin; Chapter 3 Interactions between Bleomycin and X-Irradiation; Chapter 4 Interactions between Cyclophosphamide and Radiation; Chapter 5 Useful Interactions between 5-Fluorouracil and Radiation in Man: 5-Fluorouracil as a Radiosensitizer; Chapter 6 Interaction between Microtubule Inhibitors and Ionizing Radiation; Chapter 7 Interactions between Mitomycin C and Radiation Chapter 8 Interactions between Nitrosoureas and X-IrradiationChapter 9 Interactions betweeen Cisplatin and Radiation in Experimental Rodent Tumors and Normal Tissues; Chapter 10 Interactions between Platinum Coordination Complexes and Radiation; Chapter 11 Experimental Drug-Radiation Interactions in Critical Normal Tissues; Chapter 12 In Vitro Drug-Radiation Interactions using Fractionated X-Irradiation Regimens; Chapter 13 Overview of Experimental Investigations of Interactions between Antitumor Drugs and X-Irradiation; Chapter 14 Clinical Role of Combined Chemotherapy and Radiotherapy
Series Title: CRC revivals.
Responsibility: edited by Bridget T. Hill, Angela S. Bellamy.

Abstract:

"This volume reviews the experimental data on drug-radiation interactions. Special emphasis is placed on clinically-useful antitumor drugs. Particular reference is made to appropriate timing, concentration and sequencing of drug-radiation combinations. It includes discussions on the relative merits of experimental data derived from animal versus human tumors. This book also presents a section on the potential for new model systems or alternative test procedures for evaluating therapeutic benefits and cytotoxicities. Results of randomized clinical studies are reviewed with emphasis on recent studies involving protocols specifically designed to test the benefits from optimal integration of chemotherapy with radiotherapy. This book is intended for laboratory researchers in the field and clinicians interested in using the combined modality approach. It is also a useful resource for radiologists, oncologists, and all those interested in cancer research."--Provided by publisher.

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Primary Entity

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