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Antiviral Drugs and Interferon: The Molecular Basis of Their Activity

Author: Yechiel Becker; Julia Hadar
Publisher: Boston, MA : Springer US, 1984.
Series: Developments in molecular virology, 4.
Edition/Format:   eBook : Bibliographic data : EnglishView all editions and formats
Summary:

Research on antiviral drugs and their mode of action in infected cells. Recent studies on antivirals that are activated by the herpes simplex virus type l-coded thy- midine kinase from a prod rug to  Read more...

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Genre/Form: Electronic books
Additional Physical Format: Printed edition:
Material Type: Bibliographic data, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Yechiel Becker; Julia Hadar
ISBN: 9781461338048 1461338042 9781461338062 1461338069
OCLC Number: 840282582
Description: 1 online resource (461 pages).
Contents: Introduction: Current Trends in Research on Antiviral Drugs (a Review) --
1 Introduction: Current Trends in Research on Antiviral Drugs (a Review) --
Antiherpes Simplex Virus Drugs --
2 Antiviral Activity of Iodinated Pyrimidine Deoxyribonucleosides --
3 Antiviral Properties of Aranucleosides: Metabolic Considerations --
4 Herpes Simplex Virus Thymidine Kinase-Dependent Antiviral Agents --
5 Acyclovir --
6 BVDU ((E)-5-(2-Bromovinyl)-2'-deoxyuridine) --
7 (2'-Fluoro-5-iodo-1-?-D-arabinofuranosylcytosine) (FIAC): Synthesis and Mode of Anti-Herpesvirus Activity --
8 Herpesvirus-Specified DNA Polymerase as the Target for Developing Selective Antiherpesvirus Agents --
9 Phosphonoformate and Phosphonoacetate --
10 Distamycin and Derivatives: the Pyrrole Amidine Antiviral Antibiotics --
11 Clinical Insights into the Metabolism of Arabinosyl Adenine and Interferon as Derived by Microbiological Assays --
Drugs Inhibitory to Viral Reverse Transcriptase --
12 Modulation of Retrovirus DNA Polymerase Activity by Polynucleotides and their Analogs --
Antipoxvirus Drug --
13 Antipoxvirus Activity of Isatin-?-Thiosemicarbazone (IBT) --
Drugs Affecting Synthesis or Processing of mRNA --
14 Halogenated Ribofuranosylbenzimidazoles --
15 Ribavirin --
Drugs Affecting RNA Viruses --
16 Molecular Basis of Guanidine Action --
17 Mechanism of Action of 2-(?-hydroxybenzyl)-benzimidazole (HBB) --
18 Multiple Actions of Amantadine Against Influenza Viruses --
Interferon --
19 Polynucleotide Inducers of Interferon: Studies with poly(G)-poly(C) --
20 Interferon and Interferon-like Factors in Plants --
21 The Interferon System in Man: Nature of the Interferon Molecules and Mode of Action.
Series Title: Developments in molecular virology, 4.
Responsibility: edited by Yechiel Becker, Julia Hadar.

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