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Application of peptide-based prodrug chemistry in drug development

Author: Arnab De
Publisher: New York, NY : Springer, ©2013.
Series: SpringerBriefs in pharmaceutical science & drug development.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:

Author explains the logic behind designing peptide prodrugs, synthetic procedures and bioassays to examine the conversion of the prodrug to the drug under therapeutic conditions.

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Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Arnab De
ISBN: 9781461448754 1461448751
OCLC Number: 808631518
Description: 1 online resource.
Contents: Introduction --
Application of prodrug chemistry to GLP-1 --
Experimental procedures --
Characterization of prodrugs --
Conclusion --
Appendix I. Schematic synthesis of longer acting prodrugs --
Appendix II: Structure of peptides in Table A.1 --
Appendix III: Structure of peptides in table A.2 --
Appendix IV: Structure of peptides in table A.3 --
Appendix V: Structure of peptides in table A.4 Appendix VI: Structure of peptides in table A.5 --
Appendix VII. Structure of peptides in table A.6 --
Appendix VIII: Acylataion of HO-His7, GLP(8-37) --
Appendix IX: A note on nomenclature.
Series Title: SpringerBriefs in pharmaceutical science & drug development.
Responsibility: Arnab De ; with foreword by Jean Martinez.

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