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Applied biopharmaceutics & pharmacokinetics

Author: Leon Shargel; Andrew B C Yu; Susanna Wu-Pong
Publisher: New York : McGraw-Hill Medical, 2012.
Edition/Format:   Print book : English : 6th edView all editions and formats
Summary:

A textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics. It provides you with a basic understanding of the principles of biopharmaceutics and  Read more...

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Document Type: Book
All Authors / Contributors: Leon Shargel; Andrew B C Yu; Susanna Wu-Pong
ISBN: 9780071603935 007160393X 9781259011115 1259011119
OCLC Number: 726074708
Description: xviii, 811 pages : illustrations ; 25 cm
Contents: Introduction to biopharmaceutics and pharmacokinetics --
Mathematic fundamentals in pharmacokinetics --
One-compartment open model: intravenous bolus administration --
Multicompartmental models : intravenous bolus administration --
Intravenous infusion --
Drug elimination and clearance --
Pharmacokinetics of oral absorption --
Multiple-dosage regimens --
Nonlinear pharmacokinetics --
Physiologic drug distribution and protein binding --
Drug elimination and hepatic clearance --
Pharmacogenetics --
Physiologic factors related to drug absorption --
Biopharmaceutic considerations in drug product design and in vitro drug product performance --
Drug product performance, in vivo : bioavailability and bioequivalence --
Impact of drug product quality and biopharmaceutics on clinical efficacy --
Modified-release drug products --
Targeted drug delivery systems and biotechnology products --
Relationship between pharmacokinetics and pharmacodynamics --
Application of pharmacokinetics to clinical situations --
Dosage adjustment in renal and hepatic disease --
Physiologic pharmacokinetic models, mean residence time, and statistical moment theory.
Other Titles: Applied biopharmaceutics and pharmacokinetics
Responsibility: Leon Shargel, Susanna Wu-Pong, Andrew B.C. Yu.

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