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Arenaviruses II : the Molecular Pathogenesis of Arenavirus Infections

Author: Michael B A Oldstone
Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint : Springer, 2002.
Series: Current topics in microbiology and immunology, 263.
Edition/Format:   eBook : Bibliographic data : EnglishView all editions and formats
Summary:
The second volume of Arenaviruses deals with the biology and the pathogenesis of arenaviruses primarily through the study of LCMV. Interestingly and appropriately, the fundamental observation of MHC restriction and CD8 cytotoxic T lymphocyte killing derived initially from studies with LCMV in the mouse has been expanded to studies of most human pathogens, viral, bacterial, parasitic, as well as events in cancer. The  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Printed edition:
Material Type: Bibliographic data, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Michael B A Oldstone
ISBN: 9783642560552 3642560555 9783642627248 3642627242
OCLC Number: 840292130
Description: 1 online resource (XVIII, 270 pages 49 illustrations, 4 illustrations in color.).
Contents: List of Contents --
Lymphocytic Choriomeningitis Virus and Immunology --
Innate Immune Responses to LCMV Infections: Natural Killer Cells and Cytokines --
Bystander T Cell Activation and Attrition --
Immunocytotherapy --
Mechanisms of Humoral Immunity Explored Through Studies of LCMV Infection --
Biology and Pathogenesis of Lymphocytic Choriomeningitis Virus Infection --
Contribution of LCMV Transgenic Models to Understanding T Lymphocyte Development, Activation, Tolerance, and Autoimmunity --
Regulation of Virally Induced Autoimmunity and Immunopathology: Contribution of LCMV Transgenic Models to Understanding Autoimmune Insulin-Dependent Diabetes Mellitus --
LCMV and the Central Nervous System: Uncovering Basic Principles of CNS Physiology and Virus-Induced Disease --
Contribution of LCMV Towards Deciphering Biology of Quasispecies in Vivo --
Designing Arenaviral Vaccines --
Junin Virus Vaccines.
Series Title: Current topics in microbiology and immunology, 263.
Responsibility: edited by Michael B.A. Oldstone.

Abstract:

Arenaviruses cause several human diseases known primarily as the hemorrhagic fevers occurring in South and Latin America (Bolivia: Machupo, Argentine, Junin virus, and Brazil: Sabia virus) and in  Read more...

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