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Aromatase inhibitors

Author: B J A Furr
Publisher: Basel ; Boston : Birkhäuser, ©2006.
Series: Milestones in drug therapy.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Aromatase inhibitors.
Basel ; Boston : Birkhäuser, ©2006
(DLC) 2005057021
(OCoLC)62302604
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: B J A Furr
ISBN: 9783764371999 3764371994 3764374187 9783764374181
OCLC Number: 68001205
Description: 1 online resource (ix, 182 pages) : illustrations.
Contents: Background and development of aromatase inhibitors --
Aromatase inhibitors and models for breast cancer --
Clinical pharmacology of aromatase inhibitors --
Clinical studies with exemestane --
Clinical studies with letrozole --
Clinical studies with anastrozole --
The third-generation aromatase inhibitors: a clinical overview --
Lessons from the ArKO mouse --
Possible additional therapeutic uses of aromatase inhibitors.
Series Title: Milestones in drug therapy.
Responsibility: edited by B.J.A. Furr.
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Abstract:

Many breast tumours are dependent upon oestrogen for their development and continued growth. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway  Read more...

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