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Arthritis research : methods and protocols

Author: Shun'ichi Shiozawa
Publisher: New York : Humana Press, [2014] ©2014.
Series: Methods in molecular biology (Clifton, N.J.), v. 1142.
Edition/Format:   eBook : Document : English : Second editionView all editions and formats
Database:WorldCat
Summary:
Arthritis Research: Methods and Protocols, Second Edition expands upon the first edition to present new and current techniques for the research of arthritis and related conditions. A compendium of leaders in the field contribute chapters that cover practical research methods such as the intravital multiphoton microscopy technique, techniques for evaluating exhausted CD8 T cell and for studying nucleic acid sensors  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Arthritis research.
(OCoLC)872712283
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Shun'ichi Shiozawa
ISBN: 9781493904044 1493904043 1493904035 9781493904037
OCLC Number: 876377522
Notes: Previous edition: 2007.
Includes index.
Description: 1 online resource (x, 204 pages) : illustrations (some color)
Contents: Intravital Multiphoton Microscopy for Dissecting Cellular Dynamics in Arthritic Inflammation and Bone Destruction --
Monitoring Multifunctionality of Immune-Exhausted CD8 T in Cancer Patients --
Characterization of Innate Immune Signalings Stimulated by Ligands for Pattern Recognition Receptors --
Principled for the Use of in vivo Transgene Techniques: Overview and an Introductory Practical Guide for the Selection of Tetracycline-Controlled Transgenic Mice --
Unraveling Autoimmunity with the Adoptive Transfer of T Cells from TCR-Transgenic Mice --
In Vivo Cell Transfer Assay to Detect Autoreactive T Cell Subsets --
Characterization of microRNAs and Their Targets --
Studies on the T Cell Receptor (TCR) Revision of Autoantibody-Inducing CD4T (aiCD4 T) Cell --
Basic Techniques for Studies of iNKT Cells and MAIT Cells --
Induction of de novo Autoimmune Disease in Normal Mice Upon Repeated Immunization with Antigen --
Mouse Models of Experimental Dermal Fibrosis: The Bleomycin-Induced Dermal Fibrosis --
Screening for Novel Serum Biomarker for Monitoring Disease Activity in Rheumatoid Arthritis Using iTRAQ Technology Based Quantitative Proteomic Approach --
Genome-Wide Genetic Study in Autoimmune Disease Prone Mice --
Bayesian Systems-Based Genetic Association Analysis with Effect Strength Estimation and Omic Wide Interpretation: A Case Study in Rheumatoid Arthritis --
Sample Processing, Protocol and Statistical Analysis of the Time of Flight Secondary Ion Mass Spectrometry (ToF-SIMS) of Protein, Cell and Tissue Samples --
Label-Free Imaging of Adipogenesis by Coherent Anti-Stokes Raman Scattering Microscopy.
Series Title: Methods in molecular biology (Clifton, N.J.), v. 1142.
Responsibility: edited by Shunichi Shiozawa.
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Abstract:

Arthritis Research: Methods and Protocols, Second Edition expands upon the first edition to present new and current techniques for the research of arthritis and related conditions. A compendium of leaders in the field contribute chapters that cover practical research methods such as the intravital multiphoton microscopy technique, techniques for evaluating exhausted CD8 T cell and for studying nucleic acid sensors and their effects, methods for in vivo tetracycline-controlled transgenic mice and T cell receptor transgenic mice, protocols to detect V(D)J recombination products and microRNA, and the technique to make bleomycin-induced dermal fibrosis. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Arthritis Research: Methods and Protocols, Second Edition will serve both professionals and novices with state-of-the-art techniques pertaining to this fascinating research field.

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From the book reviews: "This book offers insights and protocols regarding 16 assays used by scientists studying the workings of the immune system, particularly with respect to autoimmunity. ... It is Read more...

 
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