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Assessing quality of life in clinical trials : methods and practice

Auteur : Peter M Fayers; Ron D Hays
Éditeur : Oxford ; New York : Oxford University Press, 2005.
Édition/format :   Print book : Anglais : 2nd edVoir toutes les éditions et tous les formats
Base de données :WorldCat
Résumé :
Researchers in all clinical fields are fully aware of the importance of Quality of Life measurements in judging the efficacy of a given treatment. Psychological criteria play an important role in this evaluation. This volulme explores the current state of the art and illustrates the benefits and potential of health related quality of life assessment in clinical trials. It covers a wide range of analytical issues,  Lire la suite...
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Détails

Type d’ouvrage : Ressource Internet
Format : Livre, Ressource Internet
Tous les auteurs / collaborateurs : Peter M Fayers; Ron D Hays
ISBN : 9780198527695 0198527691
Numéro OCLC : 58997621
Notes : Revised edition of: Quality of life assessment in clinical trials / edited by Maurice J. Staquet, Ron D. Hays, and Peter M. Fayers. 1998.
Description : xiii, 467 pages : illustrations ; 25 cm
Contenu : Preface ; 1. DEVELOPING AND EVALUATING QUESTIONNAIRES ; 1.1 Generic versus disease-targeted instruments ; 1.2 Developing questionnaires ; 1.3 Reliability and validity, including responsiveness ; 1.4 Evaluating multi-item scales ; 1.5 Rasch models & IRT ; 2. ADAPTING AND USING QUESTIONNAIRES ; 2.1 Translating and evaluating questionnaires - cultural issues ; 2.2 CAT and item banking ; 2.3 Developing a questionnaire using IRT - a case study of fatigue ; 2.4 Proxy assessments and context effects ; 3. ANALYSIS ; 3.1 Analysing longitudinal studies of QOL ; 3.2 Preventing missing data ; 3.3 Analysing studies with missing data ; 3.4 Differential item functioning (DIF) for analysing cultural differences ; 3.5 Reporting analyses from clinical trials ; 4. INTERPRETING QOL IN INDIVIDUALS AND GROUPS ; 4.1 Individualised QoL ; 4.2 Meaningful differences ; 4.3 Health-related QoL outcomes in clinical trials ; 4.4 Response shift ; 4.5 Individual patient monitoring ; 5. MEASURES FOR CLINICAL TRIALS ; 5.1 Self-rated health ; 5.2 Generic adult health status measures ; 5.3 Measurement of HRQL in child/adolescent clinical trials ; 5.4 Developing disease-targeted measures for neurolgic conditions ; 6. BEYOND CLINICAL TRIALS ; 6.1 Values and valuation ; 6.2 Preference-based measures ; 6.3 Discrete choice experiments ; 6.4 Combining clinical trials - meta analysis
Autres titres : Quality of life assessment in clinical trials.
Responsabilité : edited by Peter Fayers and Ron Hays.
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Résumé :

Explores and illustrates the benefits and potential of health related quality of life assessment in clinical trials. This title covers a range of analytical issues, emphasizing innovative approaches  Lire la suite...

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This book is clearly written, resource-rich, and eloquently blends both traditional and innovative approaches to measuring HRQoL in clinical trials... Fayers and Hays' new edition encapsulates the Lire la suite...

 
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