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Assessing quality of life in clinical trials : methods and practice

Autore: Peter M Fayers; Ron D Hays
Editore: Oxford ; New York : Oxford University Press, 2005.
Edizione/Formato:   Libro : English : 2nd edVedi tutte le edizioni e i formati
Banca dati:WorldCat
Sommario:
Researchers in all clinical fields are fully aware of the importance of Quality of Life measurements in judging the efficacy of a given treatment. Psychological criteria play an important role in this evaluation. This volulme explores the current state of the art and illustrates the benefits and potential of health related quality of life assessment in clinical trials. It covers a wide range of analytical issues,  Per saperne di più…
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Tipo materiale: Risorsa internet
Tipo documento: Book, Internet Resource
Tutti gli autori / Collaboratori: Peter M Fayers; Ron D Hays
ISBN: 9780198527695 0198527691
Numero OCLC: 58997621
Note: Rev. ed. of: Quality of life assessment in clinical trials / edited by Maurice J. Staquet, Ron D. Hays, and Peter M. Fayers. 1998.
Descrizione: xiii, 467 p. : ill., ; 25 cm.
Contenuti: Preface ; 1. DEVELOPING AND EVALUATING QUESTIONNAIRES ; 1.1 Generic versus disease-targeted instruments ; 1.2 Developing questionnaires ; 1.3 Reliability and validity, including responsiveness ; 1.4 Evaluating multi-item scales ; 1.5 Rasch models & IRT ; 2. ADAPTING AND USING QUESTIONNAIRES ; 2.1 Translating and evaluating questionnaires - cultural issues ; 2.2 CAT and item banking ; 2.3 Developing a questionnaire using IRT - a case study of fatigue ; 2.4 Proxy assessments and context effects ; 3. ANALYSIS ; 3.1 Analysing longitudinal studies of QOL ; 3.2 Preventing missing data ; 3.3 Analysing studies with missing data ; 3.4 Differential item functioning (DIF) for analysing cultural differences ; 3.5 Reporting analyses from clinical trials ; 4. INTERPRETING QOL IN INDIVIDUALS AND GROUPS ; 4.1 Individualised QoL ; 4.2 Meaningful differences ; 4.3 Health-related QoL outcomes in clinical trials ; 4.4 Response shift ; 4.5 Individual patient monitoring ; 5. MEASURES FOR CLINICAL TRIALS ; 5.1 Self-rated health ; 5.2 Generic adult health status measures ; 5.3 Measurement of HRQL in child/adolescent clinical trials ; 5.4 Developing disease-targeted measures for neurolgic conditions ; 6. BEYOND CLINICAL TRIALS ; 6.1 Values and valuation ; 6.2 Preference-based measures ; 6.3 Discrete choice experiments ; 6.4 Combining clinical trials - meta analysis
Altri titoli: Quality of life assessment in clinical trials.
Responsabilità: edited by Peter Fayers and Ron Hays.
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Explores and illustrates the benefits and potential of health related quality of life assessment in clinical trials. This title covers a range of analytical issues, emphasizing innovative approaches  Per saperne di più…

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This book is clearly written, resource-rich, and eloquently blends both traditional and innovative approaches to measuring HRQoL in clinical trials... Fayers and Hays' new edition encapsulates the Per saperne di più…

 
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