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Attempts to Understand Metastasis Formation III : Therapeutic Approaches for Metastasis Treatment

Author: U Günthert; Peter M Schlag; Walter Birchmeier
Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 1996.
Series: Current topics in microbiology and immunology, 213/3.
Edition/Format:   eBook : Bibliographic data : EnglishView all editions and formats
Summary:
Within the last decade the molecular biology of tumor models has revealed the identification of several metastasis- related molecules. These volumes attempt to review the most recent approaches of their mechanisms, regulation and way to treat their malignant alterations. The first volume covers the presentation of proteases and inhibitors and their role in invasion of tumor cells, also cell adhesion molecules and  Read more...
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Details

Genre/Form: Electronic books
Additional Physical Format: Printed edition:
Material Type: Bibliographic data, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: U Günthert; Peter M Schlag; Walter Birchmeier
ISBN: 9783642800719 3642800718 9783642800733 3642800734
OCLC Number: 840300859
Description: 1 online resource (XVI, 262 pages 14 illustrations).
Contents: List of Contents --
Micrometastasis Detection and Treatment with Monoclonal Antibodies --
Transcriptionally Targeted Gene Therapy --
Recombinant Antibody Fusion Proteins for Cancer Immunotherapy --
Influence of Local Cytokines on Tumor Metastasis: Using Cytokine Gene-Transfected Tumor Cells as Experimental Models --
Antitumor and Antimetastatic Activity of lnterleukin-12 --
Curing Metastases? Gene and Peptide Therapy --
Effect of Antisense Inhibition of Urokinase Receptor on Malignancy --
Intervention in Receptor Tyrosine Kinase-Mediated Pathways: Recombinant Antibody Fusion Proteins Targeted to ErbB2 --
Interactions Between CD44 and Hyaluronic Acid: Their Role in Tumor Growth and Metastasis --
Does Soluble CD44 Reflect the Clinical Behavior of Human Cancer? --
Signal Transduction as a Therapeutic Target --
Immunotherapy of Metastases --
Immunological and Biochemical Modulation in the Treatment of Advanced Colorectal Cancer: Update and Future Directions --
Surgical and Multimodality Approaches to Liver Metastases.
Series Title: Current topics in microbiology and immunology, 213/3.
Responsibility: edited by Ursula Günthert, Peter M. Schlag, Walter Birchmeier.

Abstract:

Within the last decade the molecular biology of tumor models has revealed the identification of several metastasis- related molecules. These volumes attempt to review the most recent approaches of their mechanisms, regulation and way to treat their malignant alterations. The first volume covers the presentation of proteases and inhibitors and their role in invasion of tumor cells, also cell adhesion molecules and their interaction with the extracellular matrix. In the second volume the regulation of tumor progression and angiogenesis by cytokines, growth factors and motility factors is outlined. The third volume deals with detection of micrometastases and therapeutic approaches, such as immunotherapy, gene therapy, chemotherapy and surgical strategies to combat metastatic spread.

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