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Biocatalysis for the pharmaceutical industry : discovery, development, and manufacturing

Author: Junhua Tao; Guoqiang Lin; A Liese
Publisher: Singapore ; Hoboken, NJ : John Wiley & Sons Asia, ©2009.
Edition/Format:   Print book : EnglishView all editions and formats
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Concise yet comprehensive and systematic discussion with latest developments in genomics and proteomics. Coverage on emerging fields such as metabolic engineering, combinatorial biosysnthesis and  Read more...

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Document Type: Book
All Authors / Contributors: Junhua Tao; Guoqiang Lin; A Liese
ISBN: 9780470823149 0470823143
OCLC Number: 230181037
Description: x, 324 pages : illustrations ; 26 cm
Contents: Enzymes and their synthetic applications --
Expression hosts for enzyme discovery and production --
Directed enzyme evolution and high-throughput screening --
Applications of reaction engineering to industrial biotransformations --
Chiral synthesis of pharmaceutical intermediates using oxynitrilases --
Expanding the scope of aldolases as tools for organic synthesis --
Synthetic applications of ketoreductases and alcohol oxidases --
Applications of nitrile hydratases and nitrilases --
Biosynthesis of drug metabolites --
Application of whole-cell biotransformation in the pharmaceutical industry --
Combinatorial biosynthesis of pharmaceutical natural products --
Metabolitic engineering for the development and manufacturing of pharmaceuticals --
Multimodular synthases and supporting enzymes for chemical production --
Green chemistry with biocatalysis for production of pharmaceuticals.
Responsibility: Junhua Tao, Guoqiang Lin, Andreas Liese.

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