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Biocompatible nanomaterials for targeted and controlled delivery of biomacromolecules

Author: Deepak N Kapoor; Sanju Dhawan
Publisher: New York, N.Y. : ASME ; New York, N.Y. (222 East 46th Street, New York, NY 10017) : Momentum Press, 2013.
Series: Biomedical & nanomedical technologies.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Nanomaterials are organic or inorganic entities employed for the construction of various nanostructured devices or systems with nanometric dimensions. These nanostructures may include nanoparticles, nanowires, nanotubes, nanocapsules, nanocomposites as well as nanoporous solids. Nanomaterials have gained immense recognition, particularly in biomacromolecular delivery, owing to their capability of controlling the  Read more...
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Details

Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Deepak N Kapoor; Sanju Dhawan
ISBN: 9781606506028 1606506021
OCLC Number: 844954577
Notes: Title from PDF title page (viewed on May 29, 2013).
Description: 1 online resource (47 pages) : illustrations.
Contents: 1. Nanomaterials: a brief introduction. 2. Tissue and blood-material interactions --
2.1 Tissue response --
2.2 Blood response --
2.3 Cellular response. 3. Biocompatibility. 4. Biodegradation. 5. Biocompatible and biodegradable nanomaterials --
5.1 Organic nanomaterials --
5.1.1 Natural and modified natural nanomaterials --
5.1.2 Synthetic polymeric nanomaterials --
5.2 Stealth nanomaterials --
5.3 Inorganic nanomaterials --
5.3.1 Carbon nanotubes (CNTs) --
5.3.2 Quantum dots (QDs) --
5.3.3 End-capped mesoporous silica nanoparticles --
5.4 Metal nanoparticles --
5.4.1 Gold nanoparticles (Au-Nps) --
5.4.2 Silver nanoparticles --
5.5 Magnetic nanoparticles --
5.6 Nanocomposites, nanofibres and nanowires --
5.7 Hybrid nanomaterials --
5.8 Virus-like nanocarriers --
5.9 Multifunctional nanoparticles. 6. Biomacromolecules --
6.1 Cell penetrating peptides in biomacromolecular delivery --
6.2 Targeted biomacromolecular delivery. 7. Challenges in biomacromolecular delivery. 8. Preparation techniques of biocompatible nanostructures --
8.1 Top-down techniques --
8.1.1 Dispersion of preformed polymers --
8.1.2 Polymerization methods --
8.1.3 Ionic gelation method for hydrophilic polymers --
8.1.4 Hybrid assemblies --
8.2 Bottom-up techniques --
8.3 Scalable methods. 9. Characterization and evaluation --
9.1 Drug-polymer compatibility --
9.2 Particle size and shape --
9.3 Zeta potential --
9.4 Drug release evaluation --
9.5 Conformational stability --
9.6 Biocompatibility studies --
9.7 Pre-clinical evaluation. 10. Regulatory perspectives. 11. Industrial viability. 12. Conclusions --
References.
Series Title: Biomedical & nanomedical technologies.
Responsibility: Deepak N. Kapoor and Sanju Dhawan.

Abstract:

Nanomaterials have gained immense recognition, particularly in biomacromolecular delivery, owing to their capability of diagnosis, controlled drug release or targeting at molecular, cellular and  Read more...

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