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Bioconductor case studies

Author: Florian Hahne
Publisher: New York, NY : Springer, ©2008.
Series: Use R.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include @* import and preprocessing of  Read more...
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Genre/Form: Electronic books
Lehrbuch
Additional Physical Format: Print version:
Bioconductor case studies.
New York, NY : Springer, ©2008
(DLC) 2008926129
(OCoLC)213855651
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Florian Hahne
ISBN: 9780387772400 0387772405 1283250942 9781283250948
OCLC Number: 649423526
Description: 1 online resource (x, 283 pages) : illustrations (some color).
Contents: The ALL data set --
R and Bioconductor introduction --
Processing affymetrix expression data --
Two color arrays --
Fold changes, log-ratios, background correction, shrinkage estimation and variance stabilization --
Easy differential expression --
Differential expression --
Annotation and metadata --
Supervised machine learning --
Unsupervised machine learning --
Using graphs for interactome data --
Graph layout --
Gene set enrichment analysis --
Hypergeometric testing used for gene set enrichment analysis --
Solutions to exercises --
References --
Index.
Series Title: Use R.
Responsibility: Florian Hahne [and others].
More information:

Abstract:

In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Each chapter describes an analysis of real data using  Read more...

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From the reviews:"This work has extended R substantially and is an important tool for research. ... All the code, including solutions to the exercises, is available for downloading on the Web Read more...

 
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