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The biology and pathology of innate immunity mechanisms

Author: Yona Keisari; Itzhak Ofek
Publisher: New York : Kluwer Academic/Plenum, ©2000.
Series: Advances in experimental medicine and biology, v. 479.
Edition/Format:   Print book : Conference publication : EnglishView all editions and formats
Database:WorldCat
Summary:
This book is the proceedings of the Bathsheva de Rothschild Seminar on Innate Immunity, held on October 10-15, 1999, in Zichron Yaakov, Israel. In recent years, scientific attention has focused increasingly on immediate defense mechanisms based on non-clonal recognition of microbial components. These mechanisms constitute the innate immunity arm of the body's defense. Identification of pathogens by these mechanisms  Read more...
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Genre/Form: Congresses
Conference papers and proceedings
Congrès
Material Type: Conference publication, Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Yona Keisari; Itzhak Ofek
ISBN: 0306464098 9780306464096
OCLC Number: 44533899
Notes: "Proceedings of the Bathsheva de Rothschild Seminar on Innate Immunity, held October 10-15, 1999 in Zichron Yaakov, Israel"--Title page verso.
Description: x, 328 pages : illustrations ; 26 cm.
Contents: pt. 1. Pattern recognition, receptors and collectins in innate immunity --
Mannose receptor and scavenger receptor: two macrophage pattern recognition receptors with diverse functions in tissue homeostasis and host defense / S.A. Linehan --
Complement receptor 3 (CR3): a public transducer of innate immunity signals in macrophages / E. Yefenof --
The role of C-type lectins in the innate immunity against pulmonary pathogens / I. Ofek --
Modulation of nitric oxide production by lung surfactant in alveolar macrophages / M. Kalina --
Development of chimeric collectins with enhanced activity against influenza A virus / K.L. Hartshorn --
Initial steps in Streptococcus pneumoniae interaction with and pathogenicity to the host / M. Shani-Sekler --
pt. 2. Host cells and cytokines in innate immunity --
Role of cytokines in the maturation and function of macrophages: effect of GM-CSF and IL-4 / Y. Keisari --
Mast cell modulation of the innate immune response to enterobacterial infection / S.N. Abraham --
The NADPH oxidase diaphorase activity in permeablilized human neutrophils and granulocytic like PLB-985 cells / I. Pessach --
Activation of cytosolic phospholipase A2 by opsonized zymosan in human neutrophils requires both ERK and p38 MAP-kinase / I. Hazan-Halevy --
Cytosolic phospholipase A2 is required for the activation of the NADPH oxidase associated H+ channel in phagocyte-like cells / R. Levy --
The role of NK cells in innate immunity / N. Lieberman --
Similarities and dissimilarities between humans and mice looking at adhesion molecules defects / A. Etzioni --
The role of dendritic cells at the early stages of Leishmania infection / H. Moll --
DNA-based vaccines: the role of dendritic cells in antigen presentation / L. Paul --
Distinct patterns of IL-1a and IL-1B distribution --
a possible basis for organ mechanisms of innate immunity / M. Hacham --
pt. 3. Antimicrobial peptides --
Structure and biology of cathelicidins / M. Zanetti --
Structure activity relationship study of polymyxin B nonapeptide / H. Tsubery --
pt. 4. Innate immunity in the compromised host --
The clinical significance of neutrophil dysfunction / B. Wolach --
Clinical significance of functional aberrations in macrophage and NK cells, in type-1 cytokines and in lectin-binding molecules / Z. Handzel --
Klebsiella infections in the immunocompromised host / H. Sahly --
pt. 5. Innate immunity components in cancer --
Macrophage-recognized molecules of aopototic cells are expressed at higher levels in AKR lymphoma of aged as compared to young mice / O. Itzhaki --
Sensitivity to macrophages decreases with tumor progression in the AKR lymphoma / T. Kaptan --
Opposing effects of IL-1a and IL-1B on malignancy patterns: tumor cell-associated IL-1a peotentiates anti-tumor immune responses and tumor regressio, whereas IL-1B potentiates invasiveness / R.N. Apte.
Series Title: Advances in experimental medicine and biology, v. 479.
Responsibility: edited by Yona Keisari and Itzhak Ofek.
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Abstract:

Scientific attention has focused on immediate defense mechanisms based on non-clonal recognition of microbial components. These mechanisms constitute the innate immunity arm of the body's defense.  Read more...

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