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Biopacemaking

Author: Jos A E Spaan
Publisher: Berlin ; New York : Springer, ©2007.
Series: Series in biomedical engineering.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

The development of a bio-engineered pacemaker is of substantial clinical and also scientific interest because it promises to overcome several limitations of electronic pacemakers.

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Additional Physical Format: Online version:
Biopacemaking.
Berlin ; New York : Springer, ©2007
(OCoLC)608127922
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Jos A E Spaan
ISBN: 9783540721093 3540721096
OCLC Number: 150414729
Notes: "Originally published as volume 45, number 2 in the journal Medical and biological engineering and computing, 2007"--Title page verso.
Description: viii, 182 pages : illustrations ; 25 cm.
Contents: Biopacemaking: Clinically Attractive, Scientifically a Challenge.- Embryological Development of Pacemaker Hierarchy and Membrane Currents Related to the Function of the Adult Sinus Node: Implications for Autonomic Modulation of Biopacemakers.- Creation of a Biological Pacemaker by Gene- or Cell-Based Approaches.- Creating a Cardiac Pacemaker by Gene Therapy.- Biological Pacemakers Based on If.- Gene Therapy to Create Biological Pacemakers.- Inhibition of Cardiomyocyte Automaticity by Electrotonic Application of Inward Rectifier Current from Kir2.1 Expressing Cells.- Propagation of Pacemaker Activity.- Computer Modelling of the Sinoatrial Node.- Application of Mesenchymal Stem Cell-Derived Cardiomyocytes as Bio-pacemakers: Current Status and Problems to Be Solved.- Enrichment of Cardiac Pacemaker-Like Cells: Neure gulin-1 and Cyclic amp Increase If-Current Density and Connexin 40 mRNA Levels in Fetal Cardiomyocytes.
Series Title: Series in biomedical engineering.
Other Titles: Medical & biological engineering & computing.
Responsibility: Jos A.E. Spaan [and others], (eds.).
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