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Biopharmaceutics modeling and simulations : theory, practice, methods, and applications

Author: Kiyohiko Sugano
Publisher: Hoboken, N.J. : John Wiley & Sons, ©2012.
Edition/Format:   Print book : EnglishView all editions and formats
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This book provides pharmaceutical professionals with essential tools for modeling biopharmaceutics. The author uses illustrations and practical problems rather than heavy math to explain the basics  Read more...

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Document Type: Book
All Authors / Contributors: Kiyohiko Sugano
ISBN: 9781118028681 1118028686
OCLC Number: 778040178
Description: xxxv, 483 pages : illustrations ; 24 cm
Contents: Introduction --
Theoretical framework I : solubility --
Theoretical framework II : dissolution --
Theoretical framework III : biological membrane permeation --
Theoretical framework IV : gastrointestinal transit models and integration --
Physiology of gastrointestinal tract and other administration sites in humans and animals --
Drug parameters --
Validation of mechanistic models --
Bioequivalence and biopharmaceutical classification system --
Dose and particle size dependency --
Enabling formulations --
Food effect --
Biopharmaceutical modeling for miscellaneous cases --
Intestinal transporters --
Strategy in drug discovery and development --
Epistemology of biopharmaceutical modeling and good simulation practice.
Responsibility: Kiyohiko Sugano.

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This book serves as an invaluable source of information for the formulation scientist, the preclinical, translational or clinical pharmacokineticist, as well as the modeling and simulation scientist. Read more...

 
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