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Biophysical characterization of proteins in developing biopharmaceuticals

Author: Damian J Houde; Steven A Berkowitz
Publisher: Amsterdam, Netherlands : Elsevier, 2015. ©2015
Edition/Format:   eBook : Document : EnglishView all editions and formats
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Biophysical characterization of proteins in developing biopharmaceuticals.
Amsterdam, Netherlands : Elsevier, ©2015
xxi, 404 pages
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Damian J Houde; Steven A Berkowitz
ISBN: 9780444595904 0444595902
OCLC Number: 891381891
Description: 1 online resource (427 pages) : illustrations
Contents: List of Contributors About the Editors Preface List of Abbreviations and Symbols I: Proteins and Biophysical Characterization in the Biopharmaceutical Industry Chapter 1 - The Complexity of Protein Structure and the Challenges it Poses in Developing Biopharmaceuticals (Steven A. Berkowitz, Damian J. Houde) Chapter 2 - Biophysical Characterization and Its Role in the Biopharmaceutical Industry (Damian J. Houde, Steven A. Berkowitz) Chapter 3 - Biopharmaceutical Industry's Biophysical Toolbox (Damian J. Houde, Steven A. Berkowitz) II: The Selected Biophysical Tools in the Biopharmaceutical Industry Chapter 4 - An Introduction and Hierarchical Organization of the Biophysical Tool in Section II (Damian J. Houde, Steven A. Berkowitz) Chapter 5 - The Value of UV, Fluorescence, and FTIR Spectroscopy in Biopharmaceutical Development (Mark Brader) Chapter 6 - Circular Dichroism Spectroscopy for Protein Characterization: Biopharmaceutical Applications (A.J. Miles, B.A. Wallace) Chapter 7 - Size-Exclusion Chromatograph (SEC) in Biopharmaceutical Process Development (Steven A. Berkowitz, Damian J. Houde) Chapter 8 - Scattering Techniques for the Characterization of Biopharmaceuticals, Pages 171-209, Lee Makowski, Steven A. Berkowitz, Damian J. Houde Chapter 9 - Characterizing Biopharmaceuticals using Analytical Ultracentrifugation (Steven A. Berkowitz, John S. Philo) Chapter 10 - Subvisible and Visible Particle Analysis in Biopharmaceutical Research and Development, Pages 261-286, Andrea Hawe, Sarah Zolls, Angelika Freitag, John F. Carpenter Chapter 11 - Differential Scanning Calorimetry in the Biopharmaceutical Sciences (Stephen J. Demarest, Verna Frasca) Chapter 12 - Biophysical Mass Spectrometry for Biopharmaceutical Process Development: Focus on Hydrogen/Deuterium Exchange (George M. Bou-Assaf, Alan G. Marshall) Chapter 13 - One- and Two-Dimensional NMR Techniques for Biopharmaceuticals (Yves Aubin, Daron I. Freedberg, David A. Keire) III: Concluding Remarks on the Biophysical Characterization of Biopharmaceuticals Chapter 14 - Biophysical Characterization: An Integral Part of the "Totality of the Evidence" Concept (Damian J. Houde, Steven A. Berkowitz) Index
Responsibility: edited by Damian J. Houde, Steven A. Berkowitz.

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