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Biophysics for therapeutic protein development

Auteur : Linda O Narhi
Éditeur : New York : Springer, ©2013.
Collection : Biophysics for the life sciences.
Édition/format :   Livre électronique : Document : EnglishVoir toutes les éditions et tous les formats
Base de données :WorldCat
Résumé :
This book can be used to provide insight into this important application of biophysics for those who are planning a career in protein therapeutic development, and for those outside this area who are interested in understanding it better. The initial chapters describe the underlying theory, and strengths and weaknesses of the different techniques commonly used during therapeutic development. The majority of the  Lire la suite...
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Détails

Genre/forme : Electronic books
Format – détails additionnels : Print version:
Narhi, Linda O.
Biophysics for Therapeutic Protein Development.
Dordrecht : Springer, ©2013
Type d’ouvrage : Document, Ressource Internet
Format : Internet Resource, Computer File
Tous les auteurs / collaborateurs : Linda O Narhi
ISBN : 9781461443162 1461443164
Numéro OCLC : 828794658
Description : 1 online resource (297 pages).
Contenu : Introduction / Linda O. Narhi --
High-Throughput Biophysical Approaches to Therapeutic Protein Development / Feng He, Vladimir I. Razinkov --
Techniques for Higher-Order Structure Determination / James Kranz, Fatma AlAzzam, Atul Saluja --
Biophysical Techniques for Protein Size Distribution Analysis / Ziping Wei, Alla Polozova --
Qualification of Biophysical Methods for the Analysis of Protein Therapeutics / Yijia Jiang, Cynthia Li, John Gabrielson --
Application of Biophysics to the Early Developability Assessment of Therapeutic Candidates and Its Application to Enhance Developability Properties / Hasige Sathish, Nicolas Angell, David Lowe --
Application of Biophysics in Formulation, Process, and Product Characterization: Selected Case Studies / Satish K. Singh, Qin Zou, Min Huang --
Biophysical Analysis in Support of Development of Protein Pharmaceuticals / Sreedhara Alavattam, Barthelemy Demeule --
Case Studies Applying Biophysical Techniques to Better Characterize Protein Aggregates and Particulates of Varying Size / Tingting Wang, Sangeeta B. Joshi --
Investigation of Nonconformance During Protein Therapeutic Manufacturing / Zai-Qing Wen, Gianni Torraca, Guiyang Li --
Higher-Order Structure and Protein Aggregate Characterization of Protein Therapeutics: Perspectives from Good Manufacturing Practices and Regulatory Guidance / Evi B. Struble, John F. Cipollo.
Titre de collection : Biophysics for the life sciences.
Responsabilité : Linda O. Narhi, editor.
Plus d’informations :

Résumé :

This book assesses techniques used in therapeutic development across the product lifecycle from early discovery through expression and purification, large scale production, formulation development,  Lire la suite...

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